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CAPZA1 Antibodies

AND CAPZA1 ELISA kits, CAPZA1 Proteins

Many biological assays use antibodies to detect CAPZA1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CAPZA1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CAPZA1 antibodies...

We validate the specificity of these antibodies to CAPZA1 by testing them on tissues known to express CAPZA1 positively and negatively. Browse below to find the CAPZA1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CAPZA1 Infographic by Boster Bio

CAPZA1 protein infographic

All CAPZA1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-CAPZA1 Antibody

Human, Mouse, Rat

WB

$405
Cat # A07665
100ul

Anti-CAPZA1 Mouse Monoclonal Antibody [Clone ID: OTI2G4]

Human, Mouse, Rat

Flow Cytometry, IHC, WB

$523
Cat # M07665
100 µl

Anti-CAPZA1 Mouse Monoclonal Antibody [Clone ID: OTI7C8]

Dog, Human, Monkey, Mouse, Rat

Flow Cytometry, WB

$523
Cat # M07665-1
100 µl

CAPZA1 (NM_006135) Human Over-expression Lysate

Human

$628
Cat # LS000829
100 µg

CAPZA1 Overview

Facts about F-actin-capping protein subunit alpha-1.

CAPZA1 3D structure

CAPZA1 3D structure. Source: alphafold

F-actin-capping protein subunit alpha-1 (CAPZA1)

F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.

May play a role in the formation of epithelial cell junctions. .

Gene Information

Human
Gene Name:	CAPZA1
Uniprot:	P52907
Entrez:	829

Gene Information

Family

Belongs to:

F-actin-capping protein alpha subunit family

Family

Alternative Names

Cap Z; CAPPA1; capping protein (actin filament) muscle Z-line, alpha 1; CapZ alpha-1; CAPZ; CAZ1; F-actin-capping protein subunit alpha-1

Molecular Weight

Mass (kDA):
32.923 kDA

Molecular Weight

Genomic Context


Human

Location:	1p13.2
Sequence:	1; NC_000001.11 (112619775..112671616)

Subcellular Localizations

Cytoplasm, cytoskeleton.

Subcellular Localization

Diseases

Malignant Neoplasms
Neoplasm Metastasis
Melanoma
Carcinoma
Neoplasms
Cell Invasion
Monosomy
Glaucoma, Open-angle
Aneuploidy
Hemolysis (disorder)
Hydatidiform Mole
Dental Plaque
Aqueous Humor Disorders

Colorectal Cancer
Esophageal Neoplasms
Primary Open Angle Glaucoma
Neuroblastoma
Cell Transformation, Neoplastic
Malignant Squamous Cell Neoplasm
Skin Neoplasms

Disease

Interacting Proteins

SH3KBP1

Interacting Proteins

Pathways

Localization
Cell Motility
Pathogenesis
Cell Adhesion
Actin Filament Capping
Actin Filament Polymerization
Chemotaxis
Barbed-end Actin Filament Capping
Translation
Phagocytosis

Cell Cycle
Regulation Of Actin Filament Polymerization
Interleukin-2 Production
Actin Nucleation

Pathways

PTMs

Acetylation

Phosphoprotein

Research Areas

Extracellular Matrix

Research Areas

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CAPZA1

References

PMID: 9331217 by Hart M.C., et al. Vertebrates have conserved capping protein alpha isoforms with specific expression patterns.

PMID: 19922875 by Derivery E., et al. The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex.