This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
2 Citations
1 Citations 3 Q&As
Facts about Calpain-2 catalytic subunit.
Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs (By similarity). .
Human | |
---|---|
Gene Name: | CAPN2 |
Uniprot: | P17655 |
Entrez: | 824 |
Belongs to: |
---|
peptidase C2 family |
Calcium-activated neutral proteinase 2; calpain 2, (m/II) large subunit; calpain 2, large [catalytic] subunit; calpain 2, large subunit; Calpain large polypeptide L2; Calpain M-type; calpain, large polypeptide L2; calpain-2 catalytic subunit; Calpain-2 large subunit; CANP 2; CANPL2CANP2; CANPml; EC 3.4.22; EC 3.4.22.53; FLJ39928; M-calpain; mCANP; millimolar-calpain
Mass (kDA):
79.995 kDA
Human | |
---|---|
Location: | 1q41 |
Sequence: | 1; NC_000001.11 (223701593..223776018) |
Ubiquitous.
Cytoplasm. Cell membrane. Translocates to the plasma membrane upon Ca(2+) binding.
Boster Bio's CAPN2 antibody is what you are looking for. This article will explain how the marker works in the lab, how it can be used, and how much it cost. This article hopefully has provided enough information to enable you to make a smart decision. Make sure to check out our other articles. We have more information about Boster Bio so you can feel more confident using it.
Research in lung cancer is seeing an increase of applications for the CAPN2 marker. This marker is related to cell proliferation and migration as well as angiogenesis. It has been shown to have intracellular localization in cell lines derived from A549-Luc tumor cells. It can also inhibit signal recovery. This study shows the potential of the CAPN2 marker for early detection of cancer. The CAPN2 kinase encodes cell proliferation and migration.
CAPN2 is located at 1q41. It is conserved in chimpanzees, Rhesus monkeys, cows, dogs, mice, zebrafish, and Rhesus monkeys. It is also found in 163 other organisms. It can be used as a diagnostic tool to detect cancer and assess a person’s response to chemotherapy. The CAPN2 mark is useful in many research fields including cancer biology, immunology, and biochemistry.
The tissue-specific expression of CAPN2 is different. CAPN2 expression levels were significantly higher in the meat-type S01 chickens that those of the MB birds. Although the gene is important for meat tenderness and postmortem muscle, it remains to be unclear what its role is. These findings could also be useful for marker-assisted chicken breeding. This marker is very sensitive and precise. It is not as precise or specific as CAPN1 and CAPN3 markers. However, it is reliable enough to be used in future studies.
The Amplicon Sequence Analysis Pipeline 2 automates several steps of the ASAN process. These include the detection of barcode orientation, selecting the best region for reads, and resampling depth. The pipeline integrates all steps and accepts multiple file format input. The output is statistical tests and community composition.
The pipeline first selects a long, high-quality region that spans half of the sequence length. It then applies a'moving-average' method to preserve good-quality bases around lower-quality ones. After that, the pipeline returns the start and end coordinates for quality trimming. This is the core pipeline. This pipeline also includes several pipelines for analyzing data.
Data is everywhere today in the information age. Data is becoming an invaluable asset for businesses. It is produced at an alarming pace and can be extremely valuable. Businesses must understand their customers in order to attract new customers and retain customers. This means analyzing customer data deeply and extracting valuable insights that will help customers have better experiences. Data analysis can help companies understand their competitors and determine where they should be focusing their efforts.
The cost of the CAPN2 marker is determined by the size and type of cancer cell. It is a highly specific test that can detect and diagnose cancer cells with a 95% accuracy rate. Although these tests can be expensive, they can help you get the best possible results from your research on cancer. You should expect to pay about $100 for the test. You should ask your doctor for a quote if you have any questions. The costs are also determined by the type of cancer and the type of tumor that has the CAPN2 marker.
The overall expression level of proteins affects the CAPN2 levels in BCCs. CAPN2 is found in a subnuclearly distributed nucleolus. It is not clear what role CAPN2 plays in the nucleus. Cell cycle dynamics affect the perinucleolar region and nucleolus. To control activity and other downstream targets, some proteins are stored in the nucleolus.
CAPN2 interacts wit LIMK1 and phosphorylates CFL1, an essential protein for cell division. Additionally, the CAPN2 enzyme cleavage activates LIMK1 (which phosphorylates CFL1) to promote cell division. CAPN2 is a biomarker that can be used to identify cancer. It is important to understand how the gene is expressed.
A series of ovarian cancers has shown that the CAPN2 marker is valid. CAPN2 is an organism that has a conserved protein product. The 1q41 locus contains the human CAPN2 protein product. Other organisms that share CAPN2 gene are chimpanzees and Rhesus monkeys.
CAPN2 protein expression can be affected by miR124 mimic. CAPN2 gene expression was decreased in cells transfected from cells with miR124. The results suggest that miR124 interacts directly to CAPN2.
PMID: 2852952 by Imajoh S., et al. Molecular cloning of the cDNA for the large subunit of the high-Ca2+- requiring form of human Ca2+-activated neutral protease.
PMID: 10944468 by Ye Z., et al. cDNA cloning by amplification of circularized first strand cDNAs reveals non-IRE-regulated iron-responsive mRNAs.
*More publications can be found for each product on its corresponding product page