CAMKK2 Antibodies

AND CAMKK2 ELISA kits, CAMKK2 Proteins

Many biological assays use antibodies to detect CAMKK2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CAMKK2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CAMKK2 antibodies...

We validate the specificity of these antibodies to CAMKK2 by testing them on tissues known to express CAMKK2 positively and negatively. Browse below to find the CAMKK2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CCN4 Next: SCGB1D2

CAMKK2 Infographic by Boster Bio

All CAMKK2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-CAMKK2 Antibody Picoband®

5 Q&As

Mouse, Rat

IHC, WB

$370
Cat # PA1497
100 μg/vial

CAMKK2 (NM_153499) Human Over-expression Lysate

Human

$960
Cat # LS010645
100 µg

CAMKK2 Overview

Facts about Calcium/calmodulin-dependent protein kinase kinase 2.

CAMKK2 3D structure. Source: alphafold

Calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2)

Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a range of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4.

Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin- binding domain are inactive.

Gene Information

Human
Gene Name:	CAMKK2
Uniprot:	Q96RR4
Entrez:	10645

Family

Belongs to:

protein kinase superfamily

Alternative Names

calcium/calmodulin-dependent protein kinase kinase 2; calcium/calmodulin-dependent protein kinase kinase 2, beta; Calcium/calmodulin-dependent protein kinase kinase beta; CaM-kinase kinase 2; CaM-kinase kinase beta; CaM-KK 2; CAMKK beta protein; CaMKK beta; CaM-KK beta; CAMKK; CAMKKBCaMKK 2; EC 2.7.11; EC 2.7.11.17; KIAA0787calcium/calmodulin-dependent protein kinase beta; MGC15254

Molecular Weight

Mass (kDA):
64.746 kDA

Genomic Context


Human

Location:	12q24.31
Sequence:	12; NC_000012.12 (121237692..121298308, complement)

Tissue Specificity

Ubiquitously expressed with higher levels in the brain. Intermediate levels are detected in spleen, prostate, thyroid and leukocytes. The lowest level is in lung.

Subcellular Localizations

Nucleus. Cytoplasm. Cell projection, neuron projection. Predominantly nuclear in unstimulated cells, relocalizes into cytoplasm and neurites after forskolin induction.

Diseases

Malignant Neoplasms
Nervousness
Neoplasms
Impaired Glucose Tolerance
Inflammation
Obesity
Anxiety Disorders
Prostatic Neoplasms
Insulin Resistance
Malignant Neoplasm Of Prostate
Cholangiocarcinoma

Learning Disorders
Sclerosis
Malnutrition
Aneuploidy
Malignant Tumor Of Cervix
Severe Combined Immunodeficiency

Pathways

Glucose Homeostasis
Cell Proliferation
Localization
Rna Interference
Anaphase
Cell Cycle
Long-term Memory
Granulocyte Differentiation
Cell Migration
Brain Development
Macroautophagy
Mating
Estrus

Insulin Secretion
Cell Development
Mitosis
Energy Homeostasis
Dna Replication
Short-term Memory
Cell Death

PTMs

Phosphorylation

Oxidation

Research Areas

Protein Kinase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CAMKK2

References

PMID: 11395482 by Hsu L.-S., et al. Human Ca2+/calmodulin-dependent protein kinase kinase beta gene encodes multiple isoforms that display distinct kinase activity.

PMID: 9822657 by Anderson K.A., et al. Components of a calmodulin-dependent protein kinase cascade. Molecular cloning, functional characterization and cellular localization of Ca2+/calmodulin-dependent protein kinase kinase beta.