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CAMK2A Antibodies
AND CAMK2A ELISA kits, CAMK2A Proteins
Many biological assays use antibodies to detect CAMK2A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CAMK2A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CAMK2A antibodies...
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CAMK2A Infographic by Boster Bio
All CAMK2A Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IP, WB
$370
Cat # M03241
100 μl
Cat # M03241
100 μl
Anti-CaMKII alpha/CAMK2A Antibody Picoband®
5 Citations 1 Q&As
Human, Mouse, Rat
ELISA, WB
$370
Cat # A03241-1
100 μg/vial
Cat # A03241-1
100 μg/vial
Human, Mouse, Rat
ELISA
$480
Cat # EKC1078
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1078
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2366
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2366
1 kit, containing two 96-well plates and all necessary reagents
Anti-CaMKII alpha/CAMK2A Antibody Picoband®
3 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A03241-2
100 μg/vial
Cat # A03241-2
100 μg/vial
Human, Mouse, Rat
IF, IHC, WB
$405
Cat # A03241-3
100ul
Cat # A03241-3
100ul
Human, Mouse, Rat
IF, IHC, WB
$482
Cat # A03241T286
100ul
Cat # A03241T286
100ul
Human, Mouse, Rat
ELISA, IHC, WB
$380
Cat # A03964T305
100ul
Cat # A03964T305
100ul
Mouse, Rat
IHC, WB
$370
Cat # M03241T286
100 µl/vial
Cat # M03241T286
100 µl/vial
CAMK2A Overview
Facts about Calcium/calmodulin-dependent protein kinase type II subunit alpha.
Calcium/calmodulin-dependent protein kinase type II subunit alpha (CAMK2A)
Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in synaptic plasticity, neurotransmitter release and long-term potentiation. Member of the NMDAR signaling complex in excitatory synapses, it regulates NMDAR-dependent potentiation of the AMPAR and therefore excitatory synaptic transmission (By similarity).
Regulates dendritic spine development (PubMed:28130356). Also regulates the migration of developing neurons (PubMed:29100089).
Gene Information
| Human | |
|---|---|
| Gene Name: | CAMK2A |
| Uniprot: | Q9UQM7 |
| Entrez: | 815 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha; calcium/calmodulin-dependent protein kinase II alpha; calcium/calmodulin-dependent protein kinase II alpha-B subunit; CaM kinase II alpha subunit; CaM Kinase II alpha; CaM kinase II subunit alpha; CAMK2A; CAMKAcalcium/calmodulin-dependent protein kinase type II subunit alpha; CaMK-II alpha subunit; CaMK-II subunit alpha; CaMKIINalpha; CaM-kinase II alpha chain; EC 2.7.11; EC 2.7.11.17; KIAA0968calcium/calmodulin-dependent protein kinase type II alpha chain
Molecular Weight
Mass (kDA):
54.088 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q32 |
| Sequence: | 5; NC_000005.10 (150219491..150290130, complement) |
Subcellular Localizations
Cell junction, synapse. Cell junction, synapse, postsynaptic density. Cell projection, dendritic spine. Cell projection, dendrite. Postsynaptic lipid rafts.
Diseases
- Nervousness
- Alzheimer's Disease
- Ischemia
- Epilepsy
- Nerve Degeneration
- Depressive Disorder
- Pain
- Cerebral Ischemia
- Malnutrition
- Brain Ischemia
- Neurofibrillary Tangles
- Neurodegenerative Disorders
Interacting Proteins
- CAMK2B
- CAMK2D
- GRIN2B
- RHOXF2
Pathways
- Transport
- Localization
- Synaptic Transmission
- Translation
- Cell Death
- Pathogenesis
- Reverse Transcription
- System Development
- Nervous System Development
- Mrna Transport
- Fear Response
- Protein Phosphorylation
- Hyperphosphorylation
PTMs
- Phosphorylation
- Cleavage
- Dephosphorylation
- Acetylation
Research Areas
- Wnt Signaling Pathway
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CAMK2A
bosterbio.com/bosterbio-gene-info-cards/CAMK2A
References
PMID: 14722083 by Gaertner T.R., et al. Comparative analyses of the three-dimensional structures and enzymatic properties of alpha, beta, gamma and delta isoforms of Ca2+- calmodulin-dependent protein kinase II.
PMID: 15312654 by Krapivinsky G., et al. SynGAP-MUPP1-CaMKII synaptic complexes regulate p38 MAP kinase activity and NMDA receptor-dependent synaptic AMPA receptor potentiation.
9 Publications of Boster CAMK2A Antibodies & ELISA Kits
- PubMed ID: 10.3892/ol.2020.12020, Mechanism of transmembrane and coiled‑coil domain 1 in the regulation of proli...
- PubMed ID: 10.3233/JAD-2012-120865, β-Asarone Inhibits Neuronal Apoptosis via the CaMKII/CREB/Bcl-2 Signaling Pathw...
- PubMed ID: 10.1155/2018/4971261, Exosomes Derived from miR-214-Enriched Bone Marrow-Derived Mesenchymal Stem Cell...
- PubMed ID: -, Meng, X.,Fu, M.,Wang, S.,Chen, W.,Wang, J.,& Zhang, N.(2021). Naringin ameliorat...
- PubMed ID: 32174475, Ma L,Chen X,Zhao B,Shi Y,Han F.Enhanced apoptosis and decreased ampa receptors a...
- PubMed ID: 27451410, Inhibition of CaMKII%u03B1 in the central nucleus of amygdala attenuates fentany...
- PubMed ID: 25010576, Anti-Epileptic Effect of Ganoderma Lucidum Polysaccharides by Inhibition of Intr...
- PubMed ID: 28489932, Li Z, Yin P, Chen J, Jin S, Liu J, Luo F. PLoS One. 2017 May 10;12(5):e0177412. ...
- PubMed ID: 20052459, Sun Z, Niu R, Su K, Wang B, Wang J, Zhang J, Wang J. Arch Toxicol. 2010 May;84(5...
*More publications can be found for each product on its corresponding product page