Cell adhesion molecule 1 Antibodies

AND CADM1 ELISA kits, Cell adhesion molecule 1 Proteins

Many biological assays use antibodies to detect Cell adhesion molecule 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cell adhesion molecule 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cell adhesion molecule 1 antibodies...

We validate the specificity of these antibodies to Cell adhesion molecule 1 by testing them on tissues known to express CADM1 positively and negatively. Browse below to find the CADM1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CADM1 Infographic by Boster Bio

All CADM1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-SynCAM/CADM1 Antibody Picoband®

3 Q&As

Human, Mouse, Rat

$370
Cat # PA2294
100 μg/vial

Anti-SynCAM/CADM1 Antibody Picoband®

1 Q&As

Human, Mouse, Rat

Flow Cytometry, WB

$370
Cat # PB9136
100 μg/vial

Anti-TSLC1 CADM1 Antibody

Human, Mouse

ELISA, IF, IHC, WB

$380
Cat # A01511
100ul

Human IGSF4A/SynCAM1 Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ9BY67
Starting from 4ug

SynCAM (CADM1) (NM_014333) Human Over-expression Lysate

Human

$960
Cat # LS023705
100 µg

CADM1 Overview

Facts about Cell adhesion molecule 1.

CADM1 3D structure. Source: alphafold

Cell adhesion molecule 1 (CADM1)

Mediates homophilic cell-cell adhesion in a Ca(2+)- independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and NECTIN3 in a Ca(2+)-independent manner.

Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.

Gene Information

Human
Gene Name:	CADM1
Uniprot:	Q9BY67
Entrez:	23705

Family

Belongs to:

nectin family

Alternative Names

BL2; Cadm1; cell adhesion molecule 1; IgSF4; IGSF4A; IGSF4ADKFZp686F1789; IGSF4immunoglobulin superfamily, member 4D variant 2; Immunoglobulin superfamily member 4; immunoglobulin superfamily, member 4; Necl-2; NECL2MGC149785; nectin-like 2; Nectin-like protein 2; RA175; sgIGSF; Spermatogenic immunoglobulin superfamily; ST17; sTSLC-1; Synaptic cell adhesion molecule; SynCAM; SynCAM1; SYNCAMMGC51880; TSLC1; TSLC-1; TSLC1/Nectin-like 2/IGSF4; Tumor suppressor in lung cancer 1SYNCAM1

Molecular Weight

Mass (kDA):
48.509 kDA

Genomic Context


Human

Location:	11q23.3
Sequence:	11; NC_000011.10 (115169236..115504428, complement)

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein. Cell junction, synapse. Localized to the basolateral plasma membrane of epithelial cells in gall bladder.

Diseases

Neoplasms
Tissue Adhesions
Malignant Neoplasms
Malignant Neoplasm Of Lung
Carcinoma
Lung Neoplasms
Non-small Cell Lung Carcinoma
Cell Transformation, Neoplastic
Neoplasm Metastasis
Adenocarcinoma
Carcinogenesis
Cell Invasion

Malignant Tumor Of Cervix
Uterine Cervical Neoplasm
Malignant Paraganglionic Neoplasm
Malignant Squamous Cell Neoplasm
Cervical Intraepithelial Neoplasia
Papillomavirus Infections
Leukemia

Interacting Proteins

PSMA6
St8sia2

Pathways

Cell Adhesion
Methylation
Pathogenesis
Cell-cell Adhesion
Dna Methylation
Gene Silencing
Cell Proliferation
Cell Cycle
Spermatogenesis
Cell Motility
Cell Migration
Localization
Cell Growth

Secretion
Oncogenesis
Pachytene
Dna Hypermethylation
Wound Healing
Demethylation
Cell Differentiation

PTMs

Methylation
Demethylation
Cleavage

Reduction
Phosphorylation
Glycosylation

Palmitoylation

Research Areas

Growth and Development
Neuronal Cell Markers
Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CADM1

References

PMID: 15893517 by Zhou Y., et al. Nectin-like molecule 1 is a protein 4.1N associated protein and recruits protein 4.1N from cytoplasm to the plasma membrane.

PMID: 22438059 by Moiseeva E.P., et al. CADM1 isoforms differentially regulate human mast cell survival and homotypic adhesion.