CACNG3 Antibodies

AND CACNG3 ELISA kits, CACNG3 Proteins

Many biological assays use antibodies to detect CACNG3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CACNG3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CACNG3 antibodies...

We validate the specificity of these antibodies to CACNG3 by testing them on tissues known to express CACNG3 positively and negatively. Browse below to find the CACNG3 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CACNG3 Infographic by Boster Bio

All CACNG3 Products

Product

Figures

Specificity

Applications

Price

CACNG3 (NM_006539) Human Over-expression Lysate

Human

$628
Cat # LS010368
100 µg

CACNG3 Overview

Facts about Voltage-dependent calcium channel gamma-3 subunit.

CACNG3 3D structure. Source: alphafold

Voltage-dependent calcium channel gamma-3 subunit (CACNG3)

Regulates the trafficking into the somatodendritic compartment and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their degrees of activation, deactivation and desensitization.

Doesn't reveal subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

Gene Information

Human
Gene Name:	CACNG3
Uniprot:	O60359
Entrez:	10368

Family

Belongs to:

PMP-22/EMP/MP20 family

Alternative Names

calcium channel, voltage-dependent, gamma subunit 3; Neuronal voltage-gated calcium channel gamma-3 subunit; voltage-dependent calcium channel gamma-3 subunit; voltage-gated calcium channel gamma subunit

Molecular Weight

Mass (kDA):
35.549 kDA

Genomic Context


Human

Location:	16p12.1
Sequence:	16; NC_000016.10 (24256335..24362412)

Subcellular Localizations

Membrane; Multi-pass membrane protein. Displays a somatodendritic localization and is excluded from axons in neurons.

Diseases

Absence Epilepsy
Epilepsy
Idiopathic Generalized Epilepsy
Epilepsy, Generalized
Caprine Arthritis-encephalitis
Involuntary Movements
Chromosomal Duplication
Atrophy
Chorea
Choroidal Neovascularization
Age Related Macular Degeneration
Acute Promyelocytic Leukemia

Geographic Atrophy
Athetosis
Movement Disorders
Pathologic Neovascularization
Paroxysmal Nonkinesigenic Dyskinesia
Dysequilibrium Syndrome

Pathways

Pathogenesis
Localization

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CACNG3

References

PMID: 10221464 by Black J.L. III, et al. Identification and cloning of putative human neuronal voltage-gated calcium channel gamma-2 and gamma-3 subunits: neurologic implications.