C8B Antibodies

AND C8B ELISA kits, C8B Proteins

Many biological assays use antibodies to detect C8B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with C8B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop C8B antibodies...

We validate the specificity of these antibodies to C8B by testing them on tissues known to express C8B positively and negatively. Browse below to find the C8B antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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C8B Infographic by Boster Bio

All C8B Products

Product

Figures

Specificity

Applications

Price

Anti-C8 beta Antibody

6 Q&As

Human, Rat

$399
Cat # A07152
100μl

Anti-C8B Antibody

Human, Mouse, Rat

$405
Cat # A07152-1
100ul

C8B Overview

Facts about Complement component C8 beta chain.

C8B 3D structure. Source: alphafold

Complement component C8 beta chain (C8B)

Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. .

Gene Information

Human
Gene Name:	C8B
Uniprot:	P07358
Entrez:	732

Family

Belongs to:

complement C6/C7/C8/C9 family

Alternative Names

complement component 8 subunit beta; complement component 8, beta polypeptide; MGC163447

Molecular Weight

Mass (kDA):
67.047 kDA

Genomic Context


Human

Location:	1p32.2
Sequence:	1; NC_000001.11 (56929207..56974383, complement)

Subcellular Localizations

Secreted.

Diseases

Infective Disorder
Meningitis
Obesity
Sclerosis
Aneurysm
Meningococcal Meningitis
Pseudorabies
Complement Deficiency
Meningococcal Infections
Infection By Cryptococcus Neoformans
Immunologic Deficiency Syndromes
Insulin Resistance

Hemolysis (disorder)
Acute-phase Reaction
Encephalitis
Encephalitis Allergic
Dysequilibrium Syndrome
Influenza
Liver Carcinoma

Pathways

Immune Response
Disease Resistance
Dna Replication
Cell Activation
Acute-phase Response
T Cell Activation
Complement Activation

Pathogenesis

PTMs

Phosphorylation
Hydroxylation
Acetylation

Oxidation
Methylation
Deamidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/C8B

References

PMID: 2820472 by Howard O.M.Z., et al. Complementary DNA and derived amino acid sequence of the beta subunit of human complement protein C8: identification of a close structural and ancestral relationship to the alpha subunit and C9.

PMID: 3651397 by Haefliger J.-A., et al. Complementary DNA cloning of complement C8 beta and its sequence homology to C9.