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- Table of Contents
, No Gclids
BID Antibodies
AND BID ELISA kits, BID Proteins
Many biological assays use antibodies to detect BID, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with BID in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop BID antibodies...
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BID Infographic by Boster Bio
All BID Products
Product
Figures
Specificity
Applications
Price
Anti-Bid Antibody Picoband®
1 Citations 16 Q&As
Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # PA2015
100 μg/vial
Cat # PA2015
100 μg/vial
Anti-BID Antibody Picoband®
8 Citations 17 Q&As
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # PB9027
100 μg/vial
Cat # PB9027
100 μg/vial
Human
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M00730
100 μl
Cat # M00730
100 μl
Mouse
$250
Cat # PROTP70444
2ug, 10ug, 1mg
Cat # PROTP70444
2ug, 10ug, 1mg
Human
Flow Cytometry
$515
Cat # A00730-Dyl488
100 μg/vial
Cat # A00730-Dyl488
100 μg/vial
Human
Flow Cytometry
$515
Cat # A00730-Dyl550
100 μg/vial
Cat # A00730-Dyl550
100 μg/vial
Human, Mouse
ELISA
$480
Cat # EKC1059
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1059
1 kit, containing one 96-well plate and all necessary reagents
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00730-1
100 μg/vial
Cat # M00730-1
100 μg/vial
Human, Monkey, Mouse
IF, IHC, WB
$523
Cat # M00730-2
100 µl
Cat # M00730-2
100 µl
BID Overview
Facts about BH3-interacting domain death agonist.
BH3-interacting domain death agonist (BID)
The major proteolytic product p15 BID allows the release of cytochrome c (By similarity). Isoform 1, isoform 2 and isoform 4 induce ICE-like proteases and apoptosis.
Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl-2.
Gene Information
| Human | |
|---|---|
| Gene Name: | BID |
| Uniprot: | P55957 |
| Entrez: | 637 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
apoptic death agonist; BH3 interacting domain death agonist; BH3-interacting domain death agonist; BID isoform ES(1b); BID isoform L(2); BID isoform Si6; BID; desmocollin type 4; FP497; Human BID coding sequence; MGC15319; MGC42355; p22 BID
Molecular Weight
Mass (kDA):
21.995 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 22q11.21 |
| Sequence: | 22; NC_000022.11 (17734138..17774665, complement) |
Tissue Specificity
Isoform 2 and isoform 3 are expressed in spleen, bone marrow, cerebral and cerebellar cortex. Isoform 2 is expressed in spleen, pancreas and placenta (at protein level). Isoform 3 is expressed in lung, pancreas and spleen (at protein level). Isoform 4 is expressed in lung and pancreas (at protein level).
Subcellular Localizations
Cytoplasm. Mitochondrion membrane. Mitochondrion outer membrane. When uncleaved, it is predominantly cytoplasmic.; [BH3-interacting domain death agonist p15]: Mitochondrion membrane. Translocates to mitochondria as an integral membrane protein.; [BH3-interacting domain death agonist p13]: Mitochondrion membrane. Associated with the mitochondrial membrane.; [Isoform 1]: Cytoplasm.; [Isoform 3]: Cytoplasm.; [Isoform 2]: Mitochondrion membrane. A significant proportion of isoform 2 localizes to mitochondria, it may be cleaved constitutively.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Leukemia
- Diabetes Mellitus
- Nausea
- Pain
- Adenocarcinoma
- Diabetes Mellitus, Non-insulin-dependent
- Inflammation
- Diarrhea
- Mammary Neoplasms
- Malignant Neoplasm Of Breast
Interacting Proteins
- AHCYL1
- BAK1
- BAX
- BCL2
- Bcl2a1
- BCL2L1
- BCL2L2
- CAV1
- MCL1
- REL
Pathways
- Cell Death
- Induction Of Apoptosis
- Cell Cycle
- Cell Proliferation
- Cell Growth
- Programmed Cell Death
- Release Of Cytochrome C From Mitochondria
- Sensitization
- Pathogenesis
- Localization
- Cell Cycle Arrest
- Apoptotic Process
- Secretion
PTMs
- Cleavage
- Phosphorylation
- Glycosylation
- Acetylation
- Dephosphorylation
- Ubiquitination
- Oxidation
- Reduction
- Myristoylation
- Methylation
Research Areas
- Apoptosis
- Cancer
- Tumor Suppressors
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BID
bosterbio.com/bosterbio-gene-info-cards/BID
References
PMID: 8918887 by Wang K., et al. BID: a novel BH3 domain-only death agonist.
PMID: 9721221 by Footz T.K., et al. The gene for death agonist BID maps to the region of human 22q11.2 duplicated in cat eye syndrome chromosomes and to mouse chromosome 6.
8 Publications of Boster BID Antibodies & ELISA Kits
- PubMed ID: 10.1016/j.tiv.2007.04.008, A cytotoxin isolated from Agkistrodon acutus snake venom induces apoptosis via F...
- PubMed ID: 33130049, Ghoneim ME,Abdallah DM,Shebl AM,El-Abhar HS. The interrupted cross-talk of infla...
- PubMed ID: 22553532, Effects of extract of Buddleja officinalis on partial inflammation of lacrimal g...
- PubMed ID: 27673564, miR-181a Induces Macrophage Polarized to M2 Phenotype and Promotes M2 Macrophage...
- PubMed ID: 25207596, NLRP3 Inflammasome Sequential Changes in?Staphylococcus aureus-Induced Mouse Mod...
- PubMed ID: 23437066, Neuroprotective Effect of Kaempferol Glycosides against Brain Injury and Neuroin...
- PubMed ID: 20211517, Wang Xb, Liu Qh, Mi N, Wang P, Tang W, Zhao Xh, Li Xj. Ultrasound Med Biol. 2010...
- PubMed ID: 25774170, Li C, Chen X, Zhang N, Song Y, Mu Y. Neural Regen Res. 2012 Feb 15;7(5):325-31. ...
*More publications can be found for each product on its corresponding product page