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BAG4 Antibodies
AND BAG4 ELISA kits, BAG4 Proteins
Many biological assays use antibodies to detect BAG4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with BAG4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop BAG4 antibodies...
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BAG4 Infographic by Boster Bio
All BAG4 Products
Product
Figures
Specificity
Applications
Price
Human
$628
Cat # LS009530
100 µg
Cat # LS009530
100 µg
BAG4 Overview
Facts about BAG family molecular chaperone regulator 4.
BAG family molecular chaperone regulator 4 (BAG4)
Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release (By similarity). Prevents constitutive TNFRSF1A signaling.
Negative regulator of PRKN translocation to damaged mitochondria. .
Gene Information
| Human | |
|---|---|
| Gene Name: | BAG4 |
| Uniprot: | O95429 |
| Entrez: | 9530 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
BAG4; BAG-4; BAG-family molecular chaperone regulator-4; Bcl-2-associated athanogene 4; BCL2-associated athanogene 4; Silencer of death domains; SODD; SODDBAG family molecular chaperone regulator 4
Molecular Weight
Mass (kDA):
49.594 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 8p11.23 |
| Sequence: | 8; NC_000008.11 (38176855..38213301) |
Subcellular Localizations
Cytoplasm.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Colonic Neoplasms
- Mammary Neoplasms
- Malignant Neoplasm Of Breast
- Cell Transformation, Neoplastic
- Leukemia
- Neoplasm Metastasis
- Epithelial Ovarian Cancer
- Ovarian Neoplasm
- Inflammation
Interacting Proteins
- DCP1A
- DCP1B
- DNAJC7
- HSPA1L
- HSPA2
- HSPA8
- TBC1D7
- TSG101
Pathways
- Cell Death
- Localization
- Transport
- Intracellular Transport
- Cell Migration
- Apoptotic Signaling Pathway
- Fertilization
- Regulation Of Gene Expression
- Metaphase
- Drug Resistance
PTMs
Research Areas
- Apoptosis
- Cancer
- Mitochondrial-Mediated Pathway
- Tumor Suppressors
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BAG4
bosterbio.com/bosterbio-gene-info-cards/BAG4
References
PMID: 9873016 by Takayama S., et al. An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators.
PMID: 9915703 by Jiang Y., et al. Prevention of constitutive TNF receptor 1 signaling by silencer of death domains.