BRMS1 Antibodies

AND BRMS1 ELISA kits, BRMS1 Proteins

Many biological assays use antibodies to detect BRMS1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with BRMS1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop BRMS1 antibodies...

We validate the specificity of these antibodies to BRMS1 by testing them on tissues known to express BRMS1 positively and negatively. Browse below to find the BRMS1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: SEPTIN9 Next: CATSPERZ

BRMS1 Infographic by Boster Bio

All BRMS1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-BRMS1 Antibody Picoband®

Human, Mouse, Rat

$370
Cat # A03587-1
100 μg/vial

Anti-BRMS-1 (E43) Antibody

Human, Mouse, Rat

IHC

$405
Cat # A03587
100ul

BRMS1 (NM_015399) Human Recombinant Protein

$813
Cat # PROTQ9HCU9
20 µg

Anti-BRMS1 Rabbit Monoclonal Antibody

Human

IP, IF, IHC, ICC, WB

$370
Cat # M03587
100 μl/vial

BRMS1 (NM_015399) Human Over-expression Lysate

Human

$628
Cat # LS025855
100 µg

BRMS1 Overview

Facts about Breast cancer metastasis-suppressor 1.

BRMS1 3D structure. Source: alphafold

Breast cancer metastasis-suppressor 1 (BRMS1)

Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA in'Lys-310'.

Promotes HDAC1 binding to promoter regions. Down- regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B.

Gene Information

Human
Gene Name:	BRMS1
Uniprot:	Q9HCU9
Entrez:	25855

Family

Belongs to:

BRMS1 family

Alternative Names

breast cancer metastasis suppressor 1; breast cancer metastasis-suppressor 1; DKFZP564A063

Molecular Weight

Mass (kDA):
28.461 kDA

Genomic Context


Human

Location:	11q13.2
Sequence:	11; NC_000011.10 (66337333..66345125, complement)

Tissue Specificity

Expression levels are higher in term placentas than in early placentas. Low levels of expression observed in normal pregnancies and in molar pregnancies.

Subcellular Localizations

Nucleus. Cytoplasm. Predominantly nuclear.

Diseases

Neoplasm Metastasis
Malignant Neoplasms
Malignant Neoplasm Of Breast
Neoplasms
Mammary Neoplasms
Carcinoma
Melanoma
Cell Invasion
Lung Neoplasms
Primary Neoplasm
Neoplasm Invasiveness
Metastatic Malignant Neoplasm To The Lymph Node

Tissue Adhesions
Tumor Progression
Carcinoma Breast Stage Iv
Metastatic Malignant Neoplasm To The Lung
Adenocarcinoma
Malignant Paraganglionic Neoplasm

Interacting Proteins

CEP70
DNAJB6
HDAC1
HDAC2
HDAC4

HDAC5
HDAC6
NMI
SMARCE1
SUDS3

Pathways

Localization
Methylation
Cell Growth
Cell Adhesion
Cell Migration
Chromatin Remodeling
Cellular Localization
Anoikis
Angiogenesis
Transport
Nuclear Export
Cell Cycle
Secretion

Cell Activation
T Cell Activation
Tube Formation
Histone Modification
Nuclear Transport
Reverse Transcription
Chemotaxis

PTMs

Methylation
Phosphorylation
Acetylation

Demethylation
Deacetylation
Ubiquitination

Research Areas

Cell Cycle and Replication

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BRMS1

References

PMID: 10850410 by Seraj M.J., et al. Functional evidence for a novel human breast carcinoma metastasis suppressor, BRMS1, encoded at chromosome 11q13.

PMID: 12414911 by Janneau J.-L., et al. Transcriptional expression of genes involved in cell invasion and migration by normal and tumoral trophoblast cells.