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Protein BRICK1 Antibodies

AND BRK1 ELISA kits, Protein BRICK1 Proteins

Many biological assays use antibodies to detect Protein BRICK1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein BRICK1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein BRICK1 antibodies...

We validate the specificity of these antibodies to Protein BRICK1 by testing them on tissues known to express BRK1 positively and negatively. Browse below to find the BRK1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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BRK1 Infographic by Boster Bio

BRK1 protein infographic

All BRK1 Products

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Product

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Specificity

Applications

Price

C3orf10 (BRK1) (NM_018462) Human Recombinant Protein

$813
Cat # PROTQ8WUW1
20 µg

C3orf10 (BRK1) (NM_018462) Human Over-expression Lysate

Human

$628
Cat # LS055845
100 µg

BRK1 Overview

Facts about Protein BRICK1.

BRK1 3D structure

BRK1 3D structure. Source: alphafold

Protein BRICK1 (BRK1)

Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex.

As component of the WAVE1 complex, required for BDNF- NTRK2 endocytic trafficking and signaling from early endosomes (By similarity). .

Gene Information

Human
Gene Name:	BRK1
Uniprot:	Q8WUW1
Entrez:	55845

Gene Information

Family

Belongs to:

BRK1 family

Family

Alternative Names

BRK1; Brk1-like; chromosome 3 open reading frame 10; hHBrk1; HSPC300; MDS027; probable protein BRICK1

Molecular Weight

Mass (kDA):
8.745 kDA

Molecular Weight

Genomic Context


Human

Location:	3p25.3
Sequence:	3; NC_000003.12 (10115675..10127190)

Subcellular Localizations

Cytoplasm, cytoskeleton.

Subcellular Localization

Diseases

Carcinoma
Malignant Neoplasms
Von Hippel-lindau Syndrome
Kidney Neoplasm
Neoplasms
Renal Cell Carcinoma
Spinocerebellar Ataxia, Autosomal Recessive 1
Lung Neoplasms
Neoplasm Metastasis
Malignant Neoplasm Of Kidney
Metastatic Malignant Neoplasm To The Lymph Node
Myeloid Leukemia, Chronic
Malignant Neoplasm Of Lung

Hemangioblastoma
Myeloid Leukemia
Nervousness
Pheochromocytoma
Embryonic Mosaic
Bulla
Cell Invasion

Disease

Interacting Proteins

DTNBP1
HSBP1
NDEL1

Interacting Proteins

Pathways

Cell Morphogenesis
Localization
Actin Nucleation
Cell Proliferation
Cell Division
Cell Growth
Transport
Intracellular Transport
Cell Migration
Trichome Branching
Cytokinesis

Cytoskeleton Organization
System Development
Nervous System Development
Invasive Growth
Rna Interference

Pathways

PTMs

Acetylation

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BRK1

References

PMID: 15070726 by Gautreau A., et al. Purification and architecture of the ubiquitous Wave complex.

PMID: 18560548 by Derivery E., et al. Free Brick1 is a trimeric precursor in the assembly of a functional wave complex.