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- Table of Contents
Facts about Bromodomain-containing protein 7.
Transcriptional corepressor which down-regulates the expression of target genes. Binds to target promoters, resulting in increased histone H3 acetylation at'Lys-9' (H3K9ac).
Mouse | |
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Gene Name: | Brd7 |
Uniprot: | O88665 |
Entrez: | 26992 |
Belongs to: |
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No superfamily |
75 kDa bromodomain protein; BP75bromodomain-containing 7; bromodomain containing 7; bromodomain-containing protein 7; CELTIX1NAG4; Protein CELTIX-1
Mass (kDA):
74 kDA
Mouse | |
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Location: | 8|8 C3 |
Sequence: | 8; |
Ubiquitous.
PMID: 10526152 by Cuppen E., et al. Identification and molecular characterization of BP75, a novel bromodomain-containing protein.
PMID: 12941796 by Kim S., et al. BP75, bromodomain-containing M(r) 75,000 protein, binds dishevelled-1 and enhances Wnt signaling by inactivating glycogen synthase kinase-3 beta.