BNIP3L Antibodies

AND BNIP3L ELISA kits, BNIP3L Proteins

Many biological assays use antibodies to detect BNIP3L, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with BNIP3L in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop BNIP3L antibodies...

We validate the specificity of these antibodies to BNIP3L by testing them on tissues known to express BNIP3L positively and negatively. Browse below to find the BNIP3L antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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BNIP3L Infographic by Boster Bio

All BNIP3L Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-BNIP3L/Nix Rabbit Monoclonal Antibody

1 Citations 1 Q&As

Human, Mouse, Rat

IHC, WB

$370
Cat # M03107
100 μl

Anti-Bnip3L Antibody

Human

ELISA, IF, IHC-P, WB

$449
Cat # A03107
0.1 mg

Anti-BNIP3L Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A03107-1
100ul

BNIP3L (NM_004331) Human Over-expression Lysate

Human

$628
Cat # LS000665
100 µg

Anti-BNIP3L Antibody Picoband®

Human, Mouse, Rat

Flow Cytometry, IF, ICC, WB

$370
Cat # A03107-3
100 μg/vial

BNIP3L Overview

Facts about BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like.

BNIP3L 3D structure. Source: alphafold

BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like (BNIP3L)

Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins.

Can conquer the suppressors BCL-2 and BCL-XL, although elevated levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3.

Gene Information

Human
Gene Name:	BNIP3L
Uniprot:	O60238
Entrez:	665

Family

Belongs to:

NIP3 family

Alternative Names

Adenovirus E1B19K-binding protein B5; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like; BCL2/adenovirus E1B 19-kd protein-interacting protein 3a; BCL2/adenovirus E1B 19kDa interacting protein 3-like; BNIP3a; BNIP3H; BNIP3L; Nip3L; NIP3-like protein X; Nix; NIXBCL2/adenovirus E1B 19kD-interacting protein 3-like

Molecular Weight

Mass (kDA):
23.93 kDA

Genomic Context


Human

Location:	8p21.2
Sequence:	8; NC_000008.11 (26383054..26413127)

Subcellular Localizations

Nucleus envelope. Endoplasmic reticulum. Mitochondrion outer membrane. Membrane; Single-pass membrane protein. Colocalizes with SPATA18 at the mitochondrion outer membrane.

Diseases

Neoplasms
Malignant Neoplasms
Hypoxia
Mammary Neoplasms
Carcinoma
Anoxia
Malignant Neoplasm Of Breast
Heart Failure
Malignant Paraganglionic Neoplasm
Neoplasm Metastasis
Cell Transformation, Neoplastic
Cardiomyopathies

Tumor Angiogenesis
Hypertrophy
Liver Carcinoma
Colorectal Cancer
Malignant Neoplasm Of Prostate
Heart Diseases
Melanoma

Interacting Proteins

ADIPOQ
ATP13A2
BAD
BCL2
BNIP3

CLEC7A
FATE1
LDLRAD1
SMCO4
TMEM11

Pathways

Cell Death
Autophagy
Cell Cycle
Response To Hypoxia
Localization
Transport
Programmed Cell Death
Angiogenesis
Cell Proliferation
Autophagic Cell Death
Induction Of Apoptosis
Methylation
Glycolysis

Aging
Cell Cycle Arrest
Senescence
Cell Growth
Mitochondrial Depolarization
Erythrocyte Differentiation
Dna Methylation

PTMs

Methylation
Phosphorylation

Cleavage
Demethylation

Deacetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BNIP3L

References

PMID: 9523198 by Matsushima M., et al. Isolation, mapping, and functional analysis of a novel human cDNA (BNIP3L) encoding a protein homologous to human NIP3.

PMID: 9867803 by Chen G., et al. Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins.

1 Publications of Boster BNIP3L Antibodies & ELISA Kits

PubMed ID: 10.1080/15548627.2020.1728096, Mutant HTT (huntingtin) impairs mitophagy in a cellular model of Huntington dise...

*More publications can be found for each product on its corresponding product page