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- Table of Contents
Facts about Vesicle transport protein SEC20.
It is for instance required for endoplasmic reticulum stress-induced apoptosis (PubMed:23896122). As a substrate of RNF185 interacting with SQSTM1, might also be involved in mitochondrial autophagy (Probable).
Human | |
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Gene Name: | BNIP1 |
Uniprot: | Q12981 |
Entrez: | 662 |
Belongs to: |
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SEC20 family |
BCL2/adenovirus E1B 19 kDa protein-interacting protein 1; BCL2/adenovirus E1B 19kDa interacting protein 1; BCL2/adenovirus E1B 19kD-interacting protein 1; Nip1; SEC20; SEC20L; Transformation-related gene 8 protein; TRG-8; vesicle transport protein SEC20
Mass (kDA):
26.132 kDA
Human | |
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Location: | 5q35.1 |
Sequence: | 5; NC_000005.10 (173144447..173164387) |
Isoform 1 is highly expressed in heart, brain, liver skeletal muscle and pancreas. Isoform 3 is moderately expressed in placenta, lung and kidney. Isoform 4 is highly expressed in testis and small intestine.
Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Mitochondrion membrane; Single-pass type IV membrane protein. Localization to the mitochondrion is regulated by RNF186.
PMID: 7954800 by Boyd J.M., et al. Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins.
PMID: 10217402 by Zhang H., et al. Novel BNIP1 variants and their interaction with BCL2 family members.