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- Table of Contents
Facts about Zinc finger protein basonuclin-1.
Required for the maintenance of spermatogenesis (By similarity). May also play a role in the differentiation of oocytes and the early development of embryos (By similarity).
Human | |
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Gene Name: | BNC1 |
Uniprot: | Q01954 |
Entrez: | 646 |
Belongs to: |
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No superfamily |
basonuclin 1; basonuclin; BNC; BSN1; HsT19447; zinc finger protein basonuclin; zinc finger protein basonuclin-1
Mass (kDA):
110.972 kDA
Human | |
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Location: | 15q25.2 |
Sequence: | 15; NC_000015.10 (83255884..83284664, complement) |
In epidermis, primarily detected in cells of the basal or immediately suprabasal layers (at protein level) (PubMed:16891417). In hair follicles, mainly expressed in the outer root sheath (at protein level) (PubMed:8034748). Expressed in epidermis, testis and foreskin, and to a lower extent in thymus, spleen, mammary glands, placenta, brain and heart (PubMed:9687312).
Nucleus. Cytoplasm. Nucleus, nucleoplasm. Relocates to the midpiece of the flagellum during late spermiogenesis in spermatids.
PMID: 1332044 by Tseng H., et al. Basonuclin: a keratinocyte protein with multiple paired zinc fingers.
PMID: 9099851 by Teumer J., et al. The human basonuclin gene.