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- Table of Contents
Facts about Flavin reductase (NADPH).
Can also reduce the complexed Fe(3+) iron to Fe(2+) in the presence of FMN and NADPH. In the liver, converts biliverdin to bilirubin.
Human | |
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Gene Name: | BLVRB |
Uniprot: | P30043 |
Entrez: | 645 |
Belongs to: |
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No superfamily |
biliverdin reductase B (flavin reductase (NADPH)); Biliverdin Reductase B; Biliverdin-IX beta-reductase; BLVRB; BVRB; BVR-B; EC 1.3.1.24; EC 1.5.1.30; flavin reductase (NADPH); flavin reductase; FLR; FLRBVRB; FR; GHBP; Green heme-binding protein; MGC117413; NADPH-dependent diaphorase; NADPH-flavin reductase; SDR43U1; short chain dehydrogenase/reductase family 43U, member 1
Mass (kDA):
22.119 kDA
Human | |
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Location: | 19q13.2 |
Sequence: | 19; NC_000019.10 (40447768..40465745, complement) |
Predominantly expressed in liver and erythrocytes. At lower levels in heart, lung, adrenal gland and cerebrum.
Cytoplasm.
PMID: 8117274 by Chikuba K., et al. Cloning and nucleotide sequence of a cDNA of the human erythrocyte NADPH-flavin reductase.
PMID: 8799475 by Komuro A., et al. Molecular cloning and expression of human liver biliverdin-IXbeta reductase.