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- Table of Contents
Facts about Protein bicaudal C homolog 1.
Putative RNA-binding protein.
Acts as a negative regulator of Wnt signaling.May be involved in regulating gene expression during embryonic development. .
Human | |
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Gene Name: | BICC1 |
Uniprot: | Q9H694 |
Entrez: | 80114 |
Belongs to: |
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BicC family |
bicaudal C homolog 1 (Drosophila); BICC; DKFZp686I21119
Mass (kDA):
104.844 kDA
Human | |
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Location: | 10q21.1 |
Sequence: | 10; NC_000010.11 (58512872..58831435) |
Cytoplasm.
PMID: 21922595 by Kraus M.R., et al. Two mutations in human BICC1 resulting in Wnt pathway hyperactivity associated with cystic renal dysplasia.
PMID: 24501278 by Lee H., et al. Exome sequencing identifies de novo gain of function missense mutation in KCND2 in identical twins with autism and seizures that slows potassium channel inactivation.