Phakinin Antibodies

AND BFSP2 ELISA kits, Phakinin Proteins

Many biological assays use antibodies to detect Phakinin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Phakinin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Phakinin antibodies...

We validate the specificity of these antibodies to Phakinin by testing them on tissues known to express BFSP2 positively and negatively. Browse below to find the BFSP2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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BFSP2 Infographic by Boster Bio

All BFSP2 Products

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Product

Figures

Specificity

Applications

Price

Anti-BFSP2 Mouse Monoclonal Antibody [Clone ID: OTI4E7]

+20

Human, Rat

IHC, WB

$523
Cat # M09124
100 µl

BFSP2 (NM_003571) Human Over-expression Lysate

Human

$628
Cat # LS008419
100 µg

BFSP2 Overview

Facts about Phakinin.

BFSP2 3D structure. Source: alphafold

Phakinin (BFSP2)

Involved in addition to lens fiber cell cytoskeleton. .

Gene Information

Human
Gene Name:	BFSP2
Uniprot:	Q13515
Entrez:	8419

Family

Belongs to:

intermediate filament family

Alternative Names

beaded filament structural protein 2, phakinin; CP47; CP49; Cytoskeletal protein, 49-kD; MGC142078; phakinin

Molecular Weight

Mass (kDA):
45.88 kDA

Genomic Context


Human

Location:	3q22.1
Sequence:	3; NC_000003.12 (133397882..133475208)

Tissue Specificity

Lens.

Subcellular Localizations

Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Expressed primarily at the plasma membrane in peripheral lens fiber cells, however also localizes to the cytoplasm in mature lens fiber cells.

Diseases

Cataract
Congenital Lamellar Cataract
Lens Opacities
Cytogenetic Abnormality
Nuclear Cataract
Blind Vision
Myopia
Microphthalmos
Leukemia, T-cell
Irido-corneal Dysgenesis
De Novo Mutation
Fibrosarcoma

Pyotraumatic Dermatitis
Cataract, Congenital, Cerulean Type 1
Retroviridae Infections
Dog Diseases
Leukemogenesis
Leukemia, Experimental

Interacting Proteins

ATF4
CDR2L
SUFU
SYCE1
USHBP1

Pathways

Cell Differentiation
Aging

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BFSP2

References

PMID: 8636093 by Hess J.F., et al. Gene structure and cDNA sequence identify the beaded filament protein CP49 as a highly divergent type I intermediate filament protein.

PMID: 10739768 by Jakobs P.M., et al. Autosomal-dominant congenital cataract associated with a deletion mutation in the human beaded filament protein gene BFSP2.