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Bestrophin-4 Antibodies

AND BEST4 ELISA kits, Bestrophin-4 Proteins

Many biological assays use antibodies to detect Bestrophin-4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Bestrophin-4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Bestrophin-4 antibodies...

We validate the specificity of these antibodies to Bestrophin-4 by testing them on tissues known to express BEST4 positively and negatively. Browse below to find the BEST4 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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BEST4 Infographic by Boster Bio

BEST4 protein infographic

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BEST4 Overview

Facts about Bestrophin-4.

BEST4 3D structure

BEST4 3D structure. Source: alphafold

Bestrophin-4 (BEST4)

Forms calcium-sensitive chloride channels. Permeable to bicarbonate.

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Gene Information

Human
Gene Name:	BEST4
Uniprot:	Q8NFU0
Entrez:	266675

Gene Information

Family

Belongs to:

bestrophin family

Family

Alternative Names

bestrophin 4; bestrophin-4; MGC126872; vitelliform macular dystrophy 2-like 2; VMD2L2

Molecular Weight

Mass (kDA):
53.497 kDA

Molecular Weight

Genomic Context


Human

Location:	1p34.1
Sequence:	1; NC_000001.11 (44782145..44792828, complement)

Tissue Specificity

Predominantly found in colon and the weakly in fetal brain, spinal cord, retina, lung, trachea, testis and placenta.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Subcellular Localization

Diseases

Age Related Macular Degeneration
Vitelliform Macular Dystrophy
Cystic Fibrosis
Fibrocystic Disease Of Pancreas
Fibrosis
Edema
Encephalitis
Inflammation

Retinal Diseases
Dystrophy

Disease

Pathways

Transport
Phagocytosis
Ion Transport
Secretion

Pathways

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BEST4

References

PMID: 12032738 by Stoehr H., et al. Three novel human VMD2-like genes are members of the evolutionary highly conserved RFP-TM family.

PMID: 12907679 by Tsunenari T., et al. Structure-function analysis of the bestrophin family of anion channels.