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Bestrophin-2 Antibodies

AND BEST2 ELISA kits, Bestrophin-2 Proteins

Many biological assays use antibodies to detect Bestrophin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Bestrophin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Bestrophin-2 antibodies...

We validate the specificity of these antibodies to Bestrophin-2 by testing them on tissues known to express BEST2 positively and negatively. Browse below to find the BEST2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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BEST2 Infographic by Boster Bio

BEST2 protein infographic

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Bestrophin 2 (BEST2) (NM_017682) Human Over-expression Lysate

Human

$960
Cat # LS054831
100 µg

BEST2 Overview

Facts about Bestrophin-2.

BEST2 3D structure

BEST2 3D structure. Source: alphafold

Bestrophin-2 (BEST2)

Forms calcium-sensitive chloride channels. Permeable to bicarbonate.

.

Gene Information

Human
Gene Name:	BEST2
Uniprot:	Q8NFU1
Entrez:	54831

Gene Information

Family

Belongs to:

bestrophin family

Family

Alternative Names

bestrophin 2; FLJ20132; vitelliform macular dystrophy 2-like 1; Vitelliform macular dystrophy 2-like protein 1; VMD2L1bestrophin-2; VMD2-like gene 1

Molecular Weight

Mass (kDA):
57.139 kDA

Molecular Weight

Genomic Context


Human

Location:	19p13.13
Sequence:	19; NC_000019.10 (12751791..12758458)

Tissue Specificity

Mainly confined to the retinal pigment epithelium and colon.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Subcellular Localization

Diseases

Intraocular Pressure Disorder
Vitelliform Macular Dystrophy
Age Related Macular Degeneration
Aqueous Humor Disorders
Glaucoma
Cystic Fibrosis
Fibrosis
Dystrophy
Disorder Of Eye
Microphthalmos
Retinal Degeneration
Edema
Scleral Diseases

Dysentery
Encephalitis
Diarrhea
Retinal Diseases
Anhidrosis
Fibrocystic Disease Of Pancreas
Salivary Gland Diseases

Disease

Pathways

Secretion
Transport
Ion Transport
Localization
Bicarbonate Transport
Gland Morphogenesis
Saliva Secretion
Phagocytosis

Anion Homeostasis
Anion Transport

Pathways

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BEST2

References

PMID: 12032738 by Stoehr H., et al. Three novel human VMD2-like genes are members of the evolutionary highly conserved RFP-TM family.

PMID: 12907679 by Tsunenari T., et al. Structure-function analysis of the bestrophin family of anion channels.