BCLAF1 Antibodies

AND BCLAF1 ELISA kits, BCLAF1 Proteins

Many biological assays use antibodies to detect BCLAF1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with BCLAF1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop BCLAF1 antibodies...

We validate the specificity of these antibodies to BCLAF1 by testing them on tissues known to express BCLAF1 positively and negatively. Browse below to find the BCLAF1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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BCLAF1 Infographic by Boster Bio

All BCLAF1 Products

Product

Figures

Specificity

Applications

Price

Anti-BTF Antibody

13 Q&As

Human, Mouse, Rat

$399
Cat # A04100
100μl

Anti-BCLAF1 Antibody

Human, Mouse, Rat

ELISA, IHC-P, WB

$449
Cat # A04100-1
0.1 mg

BTF (BCLAF1) (NM_014739) Human Over-expression Lysate

Human

$960
Cat # LS009774
100 µg

Anti-BTF Rabbit Monoclonal Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$370
Cat # M04100
100 µl/vial

BCLAF1 Overview

Facts about Bcl-2-associated transcription factor 1.

BCLAF1 3D structure. Source: alphafold

Bcl-2-associated transcription factor 1 (BCLAF1)

Death-promoting transcriptional repressor. May be involved in cyclin-D1/CCND1 mRNA stability throughout the SNARP complex which associates with the 3'end of the CCND1 gene and its mRNA.

Gene Information

Human
Gene Name:	BCLAF1
Uniprot:	Q9NYF8
Entrez:	9774

Family

Belongs to:

BCLAF1/THRAP3 family

Alternative Names

bcl-2-associated transcription factor 1; BCL2-associated transcription factor 1; Btf; BTFKIAA0164bK211L9.1

Molecular Weight

Mass (kDA):
106.122 kDA

Genomic Context


Human

Location:	6q23.3
Sequence:	6; NC_000006.12 (136256627..136289851, complement)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Cytoplasm. Nucleus. Nucleus speckle. Nucleus, nucleoplasm.

Diseases

Neoplasms
Malignant Neoplasms
Muscular Dystrophy, Emery-dreifuss
Carcinoma
Dystrophy
Muscular Dystrophy
Adenoma
Neoplasm Invasiveness
Adenocarcinoma
Malignant Paraganglionic Neoplasm
Prostatic Neoplasms
Bone Neoplasms

Malignant Neoplasm Of Prostate
Hyperplasia
Thyroid Diseases
Myeloid Leukemia, Chronic
Malignant Neoplasm Of Urinary Bladder
Carcinoma In Situ
Goiter

Interacting Proteins

BCL2
EMD

Pathways

Cell Death
Localization
Cell Proliferation
Transport
Programmed Cell Death
Lung Development
Regulation Of Gene Expression
Cell Cycle
Rna Processing
Pathogenesis
Protein Phosphorylation
Cell Activation
Cell Migration

Dna Hypermethylation
T Cell Activation
Chromosome Segregation
Cell Cycle Arrest
Induction Of Apoptosis
Dna Repair
Mastication

PTMs

Phosphorylation
Demethylation
Cleavage

Deacetylation
Acetylation
Methylation

Research Areas

Apoptosis
DNA Repair

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BCLAF1

References

PMID: 10330179 by Kasof G.M., et al. Btf, a novel death-promoting transcriptional repressor that interacts with Bcl-2-related proteins.

PMID: 15009215 by Haraguchi T., et al. Emerin binding to Btf, a death-promoting transcriptional repressor, is disrupted by a missense mutation that causes Emery-Dreifuss muscular dystrophy.