BCL9 Antibodies

AND BCL9 ELISA kits, BCL9 Proteins

Many biological assays use antibodies to detect BCL9, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with BCL9 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop BCL9 antibodies...

We validate the specificity of these antibodies to BCL9 by testing them on tissues known to express BCL9 positively and negatively. Browse below to find the BCL9 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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BCL9 Infographic by Boster Bio

All BCL9 Products

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Anti-BCL9 Antibody (N-Term)

Human, Mouse

IF, WB

$299
Cat # M04057
80 µl

BCL9 Overview

Facts about B-cell CLL/lymphoma 9 protein.

BCL9 3D structure. Source: alphafold

B-cell CLL/lymphoma 9 protein (BCL9)

Involved in signal transduction through the Wnt pathway. Promotes beta-catenin's transcriptional activity (By similarity).

Gene Information

Human
Gene Name:	BCL9
Uniprot:	O00512
Entrez:	607

Family

Belongs to:

BCL9 family

Alternative Names

B-cell CLL/lymphoma 9 protein; B-cell CLL/lymphoma 9; B-cell lymphoma 9 protein; Bcl9; Bcl-9; BCL9L; LGS; MGC131591; Protein legless homolog

Molecular Weight

Mass (kDA):
149.29 kDA

Genomic Context


Human

Location:	1q21.2
Sequence:	1; NC_000001.11 (147541501..147626217)

Tissue Specificity

Detected at low levels in thymus, prostate, testis, ovary and small intestine, and at lower levels in spleen, colon and blood.

Subcellular Localizations

Nucleus.

Diseases

Malignant Neoplasms
Neoplasms
Lymphoma
B-cell Lymphomas
Leukemia
Malignant Paraganglionic Neoplasm
Chromosomal Translocation
Colorectal Cancer
Carcinoma
Cell Invasion
Acute Lymphocytic Leukemia
Neoplasm Metastasis
Carcinogenesis

Multiple Myeloma
Cell Transformation, Neoplastic
Adenocarcinoma
Diffuse Large B-cell Lymphoma
Lymphoma, Non-hodgkin
Tumor Progression
Cytogenetic Abnormality

Interacting Proteins

CDC73
CTNNB1
PYGO1
PYGO2

Pathways

Pathogenesis
Localization
Tissue Homeostasis
Cell Adhesion
Cell Proliferation
Regeneration
Immune Response
Nuclear Import
Methylation
Angiogenesis
Transport
Gene Silencing
Stem Cell Maintenance

Neurogenesis
Cell Fate Determination
Nuclear Export
Chromatin Organization
Cell-cell Adhesion
Oncogenesis
Regulation Of Cell-cell Adhesion

PTMs

Phosphorylation

Methylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BCL9

References

PMID: 9490669 by Willis T.G., et al. Molecular cloning of translocation t(1;14)(q21;q32) defines a novel gene (BCL9) at chromosome 1q21.

PMID: 11955446 by Kramps T., et al. Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex.