BCKDK Antibodies

[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial (BCKDK)

Catalyzes the phosphorylation and inactivation of this branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways. Key enzyme that govern the activity state of the BCKD complex.

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Gene Information

Human
Gene Name:	BCKDK
Uniprot:	O14874
Entrez:	10295

Family

Belongs to:
PDK/BCKDK protein kinase family

Alternative Names

BCKDHKIN; branched chain alpha-ketoacid dehydrogenase kinase; branched chain ketoacid dehydrogenase kinase; EC 2.7.11; EC 2.7.11.4; mitochondrial

Molecular Weight

Mass (kDA):
46.36 kDA

Genomic Context

Human
Location:	16p11.2
Sequence:	16; NC_000016.10 (31108381..31117651)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Mitochondrion matrix. Mitochondrion.

Diseases

• Epilepsy
• Autistic Disorder
• Impairment (finding)
• Autism Spectrum Disorders
• Diabetes Mellitus
• Dysequilibrium Syndrome

Interacting Proteins

• STAT3

PTMs

• Phosphorylation

Research Areas

• Protein Kinase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BCKDK

Boster Bio Anti-BCKDK Marker - The Best Uses Of The BCKDK Marker

If you're interested in using the Boster Bio Anti-BCKDK Marker in your scientific research, then you've come to the right place. Here, you can find details about this product as well as its benefits and the uses for it. Scientists may submit their research to this product for specific species, samples, or applications. You can also apply for product credits. This product is accessible all over the world and is suitable for all scientists.

Boster Bio Anti-BCKDK Marker

If you need to test the activity of BCKDK in your cell culture experiments, then you may want to examine the Boster Bio Anti-BCKDK Antibody Picoband. This antibody reacts with human, mouse, and rat samples. It is available in a variety of concentrations and can be used for ELISA or WB applications. The antibody is created from a mouse that has been immunized with synthetic peptide.

Boster Bio STAT3 ELISA kits detect this protein in cells culture samples. This protein is sensitive to growth factors and cytokines, and has been linked with the development of diabetes and cancer. The antigen is extremely common in mammals and easily cross-reactive across a variety of kinds of samples. The Boster STAT3 ELISA kits contain antibodies for ELISA, IHC, and flow cytometry.

The PDK/BCKDK family of proteins encodes the mitochondrial protein that has histidine kinasedomain. BCKDK can be found in the mitrochondria matrix and contributes to the regulation of glucose metabolism. Numerous hormones, including insulin and glucocorticoids influence the expression of this protein. Boster confirmed the BCKDK label by employing a variety techniques to ensure that the antibodies perform in your test.