Protein PTHB1 Antibodies

AND BBS9 ELISA kits, Protein PTHB1 Proteins

Many biological assays use antibodies to detect Protein PTHB1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein PTHB1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein PTHB1 antibodies...

We validate the specificity of these antibodies to Protein PTHB1 by testing them on tissues known to express BBS9 positively and negatively. Browse below to find the BBS9 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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BBS9 Infographic by Boster Bio

All BBS9 Products

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Specificity

Applications

Price

BBS9 (NM_198428) Human Recombinant Protein

$1062
Cat # PROTQ3SYG4
20 µg

Anti-BBS9 Antibody Picoband®

Human, Monkey, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A07367-2
100 μg/vial

BBS9 (NM_198428) Human Over-expression Lysate

Human

$960
Cat # LS027241
100 µg

BBS9 Overview

Facts about Protein PTHB1.

BBS9 3D structure. Source: alphafold

Protein PTHB1 (BBS9)

The BBSome complex is supposed to function as a coat complex required for sorting of certain membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.

This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes expansion of the ciliary membrane.

Gene Information

Human
Gene Name:	BBS9
Uniprot:	Q3SYG4
Entrez:	27241

Family

Belongs to:

No superfamily

Alternative Names

B1; Bardet-Biedl syndrome 9 protein; Bardet-Biedl syndrome 9; C18; D1; Parathyroid hormone-responsive B1 gene protein; protein PTHB1; PTHB1MGC118917; PTH-responsive osteosarcoma B1 protein

Molecular Weight

Mass (kDA):
99.28 kDA

Genomic Context


Human

Location:	7p14.3
Sequence:	7; NC_000007.14 (33129244..33637238)

Tissue Specificity

Widely expressed. Expressed in adult heart, skeletal muscle, lung, liver, kidney, placenta and brain, and in fetal kidney, lung, liver and brain.

Subcellular Localizations

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium membrane. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite.

Diseases

Bardet-biedl Syndrome
Obesity
Learning Disabilities
Retinal Diseases
Polydactyly
Diabetes Mellitus
Retinal Dystrophies
Monosomy
Interparietal Craniosynostosis
Atresia Of Vagina
Premature Menopause
Atresia

Kidney Neoplasm
Hydrocephalus
Congenital Heart Defects
Craniosynostosis
Neoplasms
Chromosome Breakage

Interacting Proteins

BBS1
BBS10
BBS12
BBS2
BBS4

BBS5
IQCB1
LZTFL1
TTC8

Pathways

Pathogenesis

Research Areas

Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BBS9

References

PMID: 10221542 by Adams A.E., et al. Identification of a novel parathyroid hormone-responsive gene in human osteoblastic cells.

PMID: 12618763 by Vernon E.G., et al. The parathyroid hormone-responsive B1 gene is interrupted by a t(1;7)(q42;p15) breakpoint associated with Wilms' tumour.