CHMP2A Antibodies

AND CHMP2A ELISA kits, CHMP2A Proteins

Many biological assays use antibodies to detect CHMP2A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CHMP2A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CHMP2A antibodies...

We validate the specificity of these antibodies to CHMP2A by testing them on tissues known to express CHMP2A positively and negatively. Browse below to find the CHMP2A antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CHMP2A Infographic by Boster Bio

All CHMP2A Products

Product

Figures

Specificity

Applications

Price

Anti-CHMP2A Antibody

Human

$405
Cat # A07825
100ul

CHMP2A (NM_198426) Human Recombinant Protein

$1249
Cat # PROTO43633
20 µg

CHMP2A (NM_014453) Human Over-expression Lysate

Human

$628
Cat # LS027243
100 µg

CHMP2A Overview

Facts about Charged multivesicular body protein 2a.

CHMP2A 3D structure. Source: alphafold

Charged multivesicular body protein 2a (CHMP2A)

Probable core component of the endosomal sorting needed for transport complex III (ESCRT-III) that is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) which are generated by invagination and scission in the limiting membrane of the endosome and are delivered to lysosomes allowing degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids.

The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate in the invaginating membrane before the ILV is discharged.

Gene Information

Human
Gene Name:	CHMP2A
Uniprot:	O43633
Entrez:	27243

Family

Belongs to:

SNF7 family

Alternative Names

BC-2; BC2VPS2 homolog A; CHMP2a; CHMP2hVps2-1; chromatin modifying protein 2A; Chromatin-modifying protein 2a; Putative breast adenocarcinoma marker BC-2; Vacuolar protein sorting-associated protein 2-1; vps2-1; VPS2Aputative breast adenocarcinoma marker (32kD); VPS2charged multivesicular body protein 2a

Molecular Weight

Mass (kDA):
25.104 kDA

Genomic Context


Human

Location:	19q13.43
Sequence:	19; NC_000019.10 (58551566..58555624, complement)

Subcellular Localizations

Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Localizes to the midbody of dividing cells. Localized in two distinct rings on either side of the Fleming body.