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- Table of Contents
Facts about Protein BANP.
Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest and inhibits tumor growth.
Mouse | |
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Gene Name: | Banp |
Uniprot: | Q8VBU8 |
Entrez: | 53325 |
Belongs to: |
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BANP/SMAR1 family |
BEN domain containing 1; BEND1BEN domain-containing protein 1; BTG3 associated nuclear protein; Btg3-associated nuclear protein; DKFZp761H172; FLJ10177; FLJ20538; protein BANP; SMAR1Scaffold/matrix-associated region-1-binding protein; SMARBP1
Mass (kDA):
59.657 kDA
Mouse | |
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Location: | 8 E1|8 70.82 cM |
Sequence: | 8; |
Highly expressed in heart, spleen, and thymus. Isoform 1 is highly expressed in kidney, brain and testis. Isoform 3 is highly expressed in kidney and lung.
PMID: 10940556 by Birot A.-M., et al. Identification and molecular analysis of BANP.
PMID: 10950932 by Chattopadhyay S., et al. SMAR1, a novel, alternatively spliced gene product, binds the Scaffold/Matrix-associated region at the T cell receptor beta locus.