BACH1 Antibodies

Transcription regulator protein BACH1 (BACH1)

Transcriptional regulator that acts as repressor or activator, depending on the context. Binds to NF-E2 DNA binding sites.

Play important roles in coordinating transcription activation and repression by MAFK (By similarity). Together with MAF, represses the transcription of genes under the control of this NFE2L2 oxidative stress pathway (PubMed:24035498).

Gene Information

Human
Gene Name:	BACH1
Uniprot:	O14867
Entrez:	571

Family

Belongs to:
bZIP family

Alternative Names

BACH1; basic region leucine zipper transcriptional regulator BACH1; BTB and CNC homolog 1; BTB and CNC homology 1, basic leucine zipper transcription factor 1; BTB; HA2303; transcription regulator protein BACH1; transcription regulator protein10BACH-1

Molecular Weight

Mass (kDA):
81.958 kDA

Genomic Context

Human
Location:	21q21.3
Sequence:	21; NC_000021.9 (29298922..29361896)

Subcellular Localizations

Nucleus.

Diseases

• Malignant Neoplasms
• Malignant Neoplasm Of Breast
• Neoplasms
• Anemia
• Mammary Neoplasms
• Fanconi Anemia
• Malignant Neoplasm Of Ovary
• Leukemia
• Carcinoma
• Genomic Instability
• Ovarian Neoplasm
• Liver Carcinoma
• Hereditary Diseases

• Hereditary Breast Carcinoma
• Down Syndrome
• Hypoxia
• Hepatitis
• Acute Erythroblastic Leukemia
• Inflammation
• Cell Transformation, Neoplastic

Interacting Proteins

• MAF
• MAFB
• MAFG

Pathways

• Dna Repair
• Nuclear Export
• Cell Cycle
• Localization
• Dna Replication
• Pathogenesis
• Response To Oxidative Stress
• Mismatch Repair
• Transport
• Double-strand Break Repair
• Cell Proliferation
• Hypersensitivity
• Cell Cycle Checkpoint

• Cellular Senescence
• Senescence
• Aging
• Immune Response
• Regulation Of Gene Expression
• Translation
• Cell Death

PTMs

• Phosphorylation
• Ubiquitination
• Oxidation
• Methylation
• Deacetylation

• Acetylation
• Sumoylation
• Hydroxylation
• Cleavage
• Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BACH1

Boster Bio - Best Uses Of The BACh2 Marker

Boster Bio: Anti BRCA1 Monoclonal Antibody is something you might be considering buying. Before you buy, there are many things to consider. These include the history of the company and the use of the BACh2 Marker. First, you need to make sure that the product is designed to work for you. This article will explain why you should use it and what you can expect from it.

Boster Bio Anti-BRCA1 Monoclonal Antibody

Boster Bio: Anti-BRCA1 monoclonal antibody reacts to Human. It can be stored at -20°C for one year or at 4°C for one month. This antibody has been tested for its performance in immunohistochemistry, ELISA, and Western Blotting. Multiple validations have been done on the antibody, including one that blocks it from binding to a protein.

Boster Bio's primary antibodies have been proven to detect BRCA1 within a variety animals samples. Its antibodies for BRCA1 are made from rabbit and mouse tissue. These antibodies recognize BRCA1 and BARD1 heterodimers, which coordinate transcriptional regulation. They are essential for the progression of cells through the cell-cycle to mitosis.

While the BRCA1 gene is expressed in all types of breast cancer, its expression varies significantly between patients. Although the gene does not appear to be specific for any particular type of breast cancer it has been suggested that it can help with treatment decision-making. A mutation in the central region of the BRCA1 gene is also linked to breast cancers. This gene is not associated with breast cancer risk but it is associated to a higher likelihood of developing the disease.

The BRCA1–BARD1 heterodimer coordinates many cellular pathways, such as DNA damage repair, transcriptional regulation and genomic stability. The BRCA1-A complex recruits BARD1 to DNA damage sites, where it can bind to the damaged DNA. These antibodies allow researchers to detect a wide variety genetic conditions.

Boster Bio: AntiBACh2 Marker

Boster Bio Anti-BACh2 Antibody (catalog number A33956) reacts with Human. The antibody can store at -20°C for a year and at 4°C for up a month. This kit includes the blocking peptide as PBS. The cost of the blocking peptide depends on the immunogen length. The antibody can be tested on positive and negative samples. It can also be used to determine if a particular sample is positive or not.

Boster Bio: Anti BRCA1 Marker

Anti-BRCA1 antibodies are produced by rabbit polyclonal antibodies, and have been validated in Western blot and Immunohistochemistry. These antibodies are specific for BRCA1 and react with Humans, Mouses, and Rats. Boster Bio's Anti-BRCA1 Marker is available in a range of concentrations and can be purchased at a variety of prices.

Boster Bio Anti-BRCA1, Mouse anti-BRCA1Marker has been developed for research. It is a versatile tool to conduct research on the BRCA1 proteins. Researchers can perform colocalization experiments using the reagents on frozen tissues, cell culture, FFPE tissue, and cell culture. These experiments may provide new insights into BRCA1's protein function and lead to targeted therapeutics.

BRCA1 gene mutation carriers are at higher risk of developing breast carcinoma. If they are carriers of the BRCA1 mutation, their chances of developing breast carcinoma later in life are between 50-95%. The good news is that they can be protected by genetic screening and preventative surgery. Studies also showed that BRCA1 mutations, which can be harmful, may increase the risk for other types of cancer in both sexes. BRCA2 mutations are also associated with a higher chance of developing pancreatic carcinoma than the BRCA1 gene mutation.

The BRCA1 gene is one of the most important genes in the human body. Mutations in the BRCA1 gene can lead to an increase in breast and ovarian carcinoma risk. Antibodies to BRCA1 are widely available on the market and can help physicians detect cancer earlier. However, many of these antibody are poorly characterized, leading to inaccurate data. Boster Bio's Anti-BRCA1 Marker, is the most precise BRCA1 mark available.

Steven Boster's history

Steven Boster's life is full of historical landmarks. Boster was a self-described "lavatory scientist" who was known for taking science to the next level. His first products were IHC kit IHC kits, and hundreds of primary antibody. This earned him the nickname "he that converts science in a lavatory." Steven Boster had already become China's largest anti-body catalog by the end the 90s. PicoKine (tm), his own proprietary ELISA technology, was developed by Boster in recent years. This platform uses trade secrets to deliver sensitive ELISA kits.

Steve Boster was a Joliet, IL, native. He was killed in a battle against COVID-19 on June 6, 2022. He was the son of Donald Sr. and Evelyn Meier Boster. He was also an active member of Concordia Hall, Staunton. He is survived his parents, Crystal Boster and Natosha Poeck, 6 grandchildren, 4 brothers, Jack Boster, Sandra Blanton, and Sandra Blanton. He also leaves behind Lisa Milton, her daughter and son Jonathan, as well as Cory, his grandson, in Herrin (IL).