B4GALNT3 Antibodies

AND B4GALNT3 ELISA kits, B4GALNT3 Proteins

Many biological assays use antibodies to detect B4GALNT3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with B4GALNT3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop B4GALNT3 antibodies...

We validate the specificity of these antibodies to B4GALNT3 by testing them on tissues known to express B4GALNT3 positively and negatively. Browse below to find the B4GALNT3 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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B4GALNT3 Infographic by Boster Bio

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B4GALNT3 (NM_173593) Human Over-expression Lysate

Human

$960
Cat # LS283358
100 µg

B4GALNT3 Overview

Facts about Beta-1,4-N-acetylgalactosaminyltransferase 3.

B4GALNT3 3D structure. Source: alphafold

Beta-1,4-N-acetylgalactosaminyltransferase 3 (B4GALNT3)

Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and Likely O-linked glycans.
Mediates the N,N'- diacetyllactosediamine formation on gastric mucosa.

Gene Information

Human
Gene Name:	B4GALNT3
Uniprot:	Q6L9W6
Entrez:	283358

Family

Belongs to:

chondroitin N-acetylgalactosaminyltransferase family

Alternative Names

B4GalNAcT3; B4GALNT3; beta-1,4-N-acetyl-galactosaminyl transferase 3; beta-1,4-N-acetylgalactosaminyltransferase III; Beta4GalNAcT3; N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase; NGalNAc-T2

Molecular Weight

Mass (kDA):
114.975 kDA

Genomic Context


Human

Location:	12p13.33
Sequence:	12; NC_000012.12 (459939..563509)

Tissue Specificity

Highly expressed in testis, colon and stomach. Weakly expressed in other tissues.

Subcellular Localizations

Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Localizes to apical Golgi.

Diseases

Cell Invasion
Neuroblastoma
Cell Transformation, Neoplastic
Malignant Paraganglionic Neoplasm
Tissue Adhesions
Atherosclerosis
Neoplasm Invasiveness
Coronary Artery Disease
Heart Diseases

Neoplasms
Cardiac Arrest
Sudden Cardiac Death
Sudden Cardiac Arrest

Pathways

Cell Proliferation
Cell Migration

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/B4GALNT3

References

PMID: 12966086 by Sato T., et al. Molecular cloning and characterization of a novel human beta 1,4-N- acetylgalactosaminyltransferase, beta 4GalNAc-T3, responsible for the synthesis of N,N'-diacetyllactosediamine, galNAc beta 1-4GlcNAc.

PMID: 16728562 by Ikehara Y., et al. Apical Golgi localization of N,N'-diacetyllactosediamine synthase, beta4GalNAc-T3, is responsible for LacdiNAc expression on gastric mucosa.