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- Table of Contents
Facts about Beta-1,4 N-acetylgalactosaminyltransferase 1.
Involved in the biosynthesis of gangliosides GM2, GD2 and GA2.
.Human | |
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Gene Name: | B4GALNT1 |
Uniprot: | Q00973 |
Entrez: | 2583 |
Belongs to: |
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glycosyltransferase 2 family |
(N-acetylneuraminyl)-galactosylglucosylceramide; beta-1,4 N-acetylgalactosaminyltransferase 1; beta1,4GalNAc-T; beta-1,4-N-acetyl-galactosaminyl transferase 1; beta1-4GalNAc-T; GALGTEC 2.4.1.92; GALNACT; GalNAc-T; GD2 synthase, GM2 synthase; GM2/GD2 synthase; SIAT2; UDP-Gal:betaGlcNAc beta-1,4-N-acetylgalactosaminyltransferase transferase 1; UDP-N-acetyl-alpha-D-galactosamine:(N-acetylneuraminyl)-galactosylglucosylceramideN-acetylgalactosaminyltransferase (GalNAc-T)
Mass (kDA):
58.882 kDA
Human | |
---|---|
Location: | 12q13.3 |
Sequence: | 12; NC_000012.12 (57623409..57633239, complement) |
Golgi apparatus membrane; Single-pass type II membrane protein.
PMID: 1601877 by Nagata Y., et al. Expression cloning of beta 1,4 N-acetylgalactosaminyltransferase cDNAs that determine the expression of GM2 and GD2 gangliosides.
PMID: 8120069 by Nagata Y., et al. Expression cloning of beta 1,4 N-acetylgalactosaminyltransferase cDNAs that determine the expression of GM2 and GD2 gangliosides.