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- Table of Contents
Facts about Armadillo repeat-containing X-linked protein 1.
Enhances mitochondria movement and neurite growth in both mature axons and embryonic neurons. Promotes neuronal survival and axon regeneration after nerve injury.
Human | |
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Gene Name: | ARMCX1 |
Uniprot: | Q9P291 |
Entrez: | 51309 |
Belongs to: |
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eutherian X-chromosome-specific Armcx family |
ALEX1armadillo repeat-containing X-linked protein 1; ARM protein lost in epithelial cancers on chromosome X 1; arm protein lost in epithelial cancers, X chromosome, 1; armadillo repeat containing, X-linked 1; DKFZp686P06199; Protein ALEX1
Mass (kDA):
49.18 kDA
Human | |
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Location: | Xq22.1 |
Sequence: | X; NC_000023.11 (101550547..101554700) |
Expressed at high levels ovary, heart, testis, prostate, brain, spleen and colon. Expressed at very low levels in liver and thymus. Not expressed in peripheral blood leukocytes. Not or reduced expressed in lung, prostate, colon, pancreas and ovarian carcinomas.
Mitochondrion. Mitochondrion outer membrane; Single-pass membrane protein.
PMID: 11162520 by Kurochkin I.V., et al. ALEX1, a novel human armadillo repeat protein that is expressed differentially in normal tissues and carcinomas.