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- Table of Contents
Facts about Rho GTPase-activating protein 18.
Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. Acts downstream of YAP1 and inhibits actin polymerization, which then reduces nuclear localization of YAP1.
Mouse | |
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Gene Name: | Arhgap18 |
Uniprot: | Q8K0Q5 |
Entrez: | 73910 |
Belongs to: |
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No superfamily |
bA307O14.2; MacGAP; MGC126757; Rho GTPase activating protein 18; rho-type GTPase-activating protein 18
Mass (kDA):
74.93 kDA
Mouse | |
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Location: | 10|10 A4 |
Sequence: | 10; |
PMID: 21865595 by Maeda M., et al. ARHGAP18, a GTPase-activating protein for RhoA, controls cell shape, spreading, and motility.