AGXT Antibodies

AND AGXT ELISA kits, AGXT Proteins

Many biological assays use antibodies to detect AGXT, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AGXT in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AGXT antibodies...

We validate the specificity of these antibodies to AGXT by testing them on tissues known to express AGXT positively and negatively. Browse below to find the AGXT antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AGXT Infographic by Boster Bio

All AGXT Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-AGXT Antibody

Human

IHC, WB

$405
Cat # A02267
100ul

Anti-AGXT Antibody

Human

$299
Cat # M02267
50 µl

Anti-AGXT Rabbit Polyclonal Antibody

Human, Mouse, Rat

$477
Cat # A02267-1
100 µl

AGXT Overview

Facts about Serine--pyruvate aminotransferase.

AGXT 3D structure. Source: alphafold

Serine--pyruvate aminotransferase (AGXT)

Gene Information

Human
Gene Name:	AGXT
Uniprot:	P21549
Entrez:	189

Family

Belongs to:

class-V pyridoxal-phosphate-dependent aminotransferase family

Alternative Names

AGT1L-alanine: glyoxylate aminotransferase 1; AGThepatic peroxisomal alanine:glyoxylate aminotransferase; AGXT1; alanine-glyoxylate aminotransferase; Alanine--glyoxylate aminotransferase; EC 2.6.1.44; EC 2.6.1.51; PH1; serine:pyruvate aminotransferase; SPATserine-pyruvate aminotransferase; SPTserine--pyruvate aminotransferase; TLH6

Molecular Weight

Mass (kDA):
43.01 kDA

Genomic Context


Human

Location:	2q37.3
Sequence:	2; NC_000002.12 (240868824..240880500)

Tissue Specificity

Liver.

Subcellular Localizations

Peroxisome. Mitochondrion. Predominantly localized in the peroxisomes. Mitochondrial mistargeting occurs in variant proteins Arg-41, Arg-47, Ile-152, Arg-170 and Thr-244 associated with the disease HP1.

Diseases

Hyperoxaluria
Hyperoxaluria, Primary
Primary Hyperoxaluria, Type I
Kidney Failure
Kidney Failure, Chronic
Kidney Diseases
Nephrocalcinosis
Kidney Calculi
Nephrolithiasis
Urolithiasis
Hereditary Diseases
Inborn Errors Of Metabolism

Hypercalciuria
Metabolic Diseases
Hyperoxalaemia
Malnutrition
De Novo Mutation
Primary Hyperoxaluria Type 2
Uniparental Disomy

Pathways

Excretion
Translation
Transport
Oxalate Transport
Pathogenesis
Localization
Gluconeogenesis

Glycolysis
Secretion

PTMs

Cleavage

Amination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AGXT

References

PMID: 2253628 by Nishiyama K., et al. Cloning and nucleotide sequence of cDNA encoding human liver serine- pyruvate aminotransferase.

PMID: 1703535 by Purdue P.E., et al. Identification of mutations associated with peroxisome-to- mitochondrion mistargeting of alanine/glyoxylate aminotransferase in primary hyperoxaluria type 1.