Agtrap Antibodies

AND Agtrap ELISA kits, Agtrap Proteins

Many biological assays use antibodies to detect Agtrap, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Agtrap in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Agtrap antibodies...

We validate the specificity of these antibodies to Agtrap by testing them on tissues known to express Agtrap positively and negatively. Browse below to find the Agtrap antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: SEPTIN9 Next: Agxt

Agtrap Infographic by Boster Bio

All Agtrap Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-AGTRAP Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A04415
100ul

AGTRAP (NM_020350) Human Over-expression Lysate

Human

$628
Cat # LS057085
100 µg

Agtrap Overview

Facts about Type-1 angiotensin II receptor-associated protein.

Type-1 angiotensin II receptor-associated protein (Agtrap)

Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalisation as well as mechanism of receptor desensitization like phosphorylation. Induces also a reduction in angiotensin II-stimulated transcriptional activity.

May play a role of negative regulator in cardiomyocyte hypertrophy induced by angiotensin II through an inhibition of p38 mitogen-activated protein kinase pathway. .

Gene Information

Mouse
Gene Name:	Agtrap
Uniprot:	Q9WVK0
Entrez:	11610

Family

Belongs to:

No superfamily

Alternative Names

angiotensin II receptor-associated protein; AT1 receptor-associated protein; ATI receptor-associated protein; MGC29646; type I receptor-associated protein; type-1 angiotensin II receptor-associated protein

Molecular Weight

Mass (kDA):
17.525 kDA

Genomic Context


Mouse

Location:	4 E2\|4 78.67 cM
Sequence:	4;

Diseases

Hypertensive Disease
Hypertrophy
Cardiac Hypertrophy
Inflammation
Fibrosis
Ischemia
Heart Failure
Nervousness
Kidney Diseases
Disease Of Adrenal Medulla
Fetal Growth Retardation
Tumor Angiogenesis
Neoplasms

Reperfusion Injury
Stenosis
Septic Shock
Vascular System Injuries
Tissue Adhesions
Atherosclerosis
Acute Coronary Syndrome

Pathways

Pathogenesis
Cell Proliferation
Receptor Internalization
Cell Growth
Cell Adhesion
Localization
Angiogenesis
Bioluminescence
Blood Vessel Development
Aging
Proteolysis
Endothelial Microparticle Formation

Glomerular Filtration
Senescence
Regeneration
Cytokine Production
Cell Death
Vasoconstriction
Secretion

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Agtrap

References

PMID: 10358057 by Daviet L., et al. Cloning and characterization of ATRAP, a novel protein that interacts with the angiotensin II type 1 receptor.

PMID: 15757644 by Tanaka Y., et al. The novel angiotensin II type 1 receptor (AT1R)-associated protein ATRAP downregulates AT1R and ameliorates cardiomyocyte hypertrophy.