Adipor2 Antibodies

AND Adipor2 ELISA kits, Adipor2 Proteins

Many biological assays use antibodies to detect Adipor2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Adipor2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Adipor2 antibodies...

We validate the specificity of these antibodies to Adipor2 by testing them on tissues known to express Adipor2 positively and negatively. Browse below to find the Adipor2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Adipor2 Infographic by Boster Bio

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Adiponectin Receptor 2 (ADIPOR2) (NM_024551) Human Over-expression Lysate

Human

$628
Cat # LS079602
100 µg

Adipor2 Overview

Facts about Adiponectin receptor protein 2.

Adiponectin receptor protein 2 (Adipor2)

Receptor for ADIPOQ, an important hormone secreted by adipocytes that modulates glucose and lipid metabolism (PubMed:17327425, PubMed:17068142, PubMed:17268472, PubMed:24742672). Required for normal body fat and glucose homeostasis (PubMed:17327425, PubMed:17068142, PubMed:17268472, PubMed:24742672).

ADIPOQ-binding activates a signaling cascade that leads to greater PPARA action, and finally to increased fatty acid oxidation and glucose uptake (PubMed:12802337, PubMed:17268472, PubMed:24742672). Has intermediate affinity for globular and full-length adiponectin (PubMed:12802337).

Gene Information

Mouse
Gene Name:	Adipor2
Uniprot:	Q8BQS5
Entrez:	68465

Family

Belongs to:

ADIPOR family

Alternative Names

ACDCR2; adiponectin receptor 2; adiponectin receptor protein 2; AdipoR2; FLJ21432; PAQR2; PAQR2MGC4640; Progestin and adipoQ receptor family member II

Molecular Weight

Mass (kDA):
43.981 kDA

Genomic Context


Mouse

Location:	6 F1\|6 56.78 cM
Sequence:	6;

Tissue Specificity

Detected in liver and quadriceps muscle (at protein level) (PubMed:17327425). Highly expressed in liver (PubMed:12802337). Highly expressed in white adipose tissue, and at intermediate levels in brown adipose tissue (PubMed:24742672). Expressed at intermediate level in heart, kidney, lung and skeletal muscle. Weakly expressed in brain, spleen and testis.

Diseases

Obesity
Insulin Resistance
Diabetes Mellitus
Insulin Sensitivity
Diabetes Mellitus, Non-insulin-dependent
Malignant Neoplasms
Inflammation
Fatty Liver
Atherosclerosis
Liver Diseases
Neoplasms
Steatohepatitis
Steatosis

Fibrosis
Cardiovascular Diseases
Impaired Glucose Tolerance
Nonalcoholic Fatty Liver Disease
Metabolic Syndrome X
Hyperinsulinism
Nonalcoholic Steatohepatitis

Pathways

Secretion
Energy Homeostasis
Pathogenesis
Fatty Acid Oxidation
Cell Proliferation
Adiponectin Secretion
Cell Growth
Gluconeogenesis
Insulin Secretion
Rna Interference
Embryo Development
Cell Cycle
Transport

Reverse Transcription
Glucose Homeostasis
Lactation
Sensitization
Glucose Transport
Localization
Lipid Oxidation

PTMs

Phosphorylation
Oxidation
Cleavage

Reduction
Glycosylation
Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Adipor2

References

PMID: 12802337 by Yamauchi T., et al. Cloning of adiponectin receptors that mediate antidiabetic metabolic effects.

PMID: 17327425 by Bjursell M., et al. Opposing effects of adiponectin receptors 1 and 2 on energy metabolism.