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- Table of Contents
Facts about A disintegrin and metalloproteinase with thrombospondin motifs 7.
Human | |
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Gene Name: | ADAMTS7 |
Uniprot: | Q9UKP4 |
Entrez: | 11173 |
Belongs to: |
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No superfamily |
A disintegrin and metalloproteinase with thrombospondin motifs 7; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondintype 1 motif, 7; ADAM metallopeptidase with thrombospondin type 1 motif, 7; ADAM-TS 7; ADAMTS-7; ADAM-TS7a disintegrin and metalloprotease with thrombospondin motifs-7 preproprotein; COMPase; DKFZp434H204; EC 3.4.24; EC 3.4.24.-; EC 3.4.24.82
Mass (kDA):
184.095 kDA
Human | |
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Location: | 15q25.1 |
Sequence: | 15; NC_000015.10 (78759203..78811476, complement) |
Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Detected in meniscus, bone, tendon, cartilage, synovium, fat and ligaments.
Secreted, extracellular space, extracellular matrix. Also found associated with the external cell surface.
PMID: 16585064 by Liu C.-J., et al. ADAMTS-7: a metalloproteinase that directly binds to and degrades cartilage oligomeric matrix protein.
PMID: 10464288 by Hurskainen T.L., et al. ADAM-TS5, ADAM-TS6, and ADAM-TS7, novel members of a new family of zinc metalloproteases.