Atf7ip Antibodies

AND Atf7ip ELISA kits, Atf7ip Proteins

Many biological assays use antibodies to detect Atf7ip, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Atf7ip in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Atf7ip antibodies...

We validate the specificity of these antibodies to Atf7ip by testing them on tissues known to express Atf7ip positively and negatively. Browse below to find the Atf7ip antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Atf7ip Infographic by Boster Bio

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Atf7ip Overview

Facts about Activating transcription factor 7-interacting protein 1.

Activating transcription factor 7-interacting protein 1 (Atf7ip)

Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context.

Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. Required to stimulate histone methyltransferase activity of SETDB1 and facilitate the conversion of dimethylated into trimethylated H3'Lys-9' (H3K9me3).

Gene Information

Mouse
Gene Name:	Atf7ip
Uniprot:	Q7TT18
Entrez:	54343

Family

Belongs to:

MCAF family

Alternative Names

activating transcription factor 7 interacting protein; activating transcription factor 7-interacting protein 1; ATF7-interacting protein; ATFa-associated modulator; ATF-interacting protein; ATF-IP; FLJ10139; FLJ10688; hAM; MBD1-containing chromatin associated factor; MCAF1AM; MCAFMBD1-containing chromatin-associated factor 1; MMCP 6; MMCP6; MMCP-6; p621

Molecular Weight

Mass (kDA):
138.593 kDA

Genomic Context


Mouse

Location:	6\|6 G1
Sequence:	6;

Tissue Specificity

Ubiquitously expressed at all stages studied.

Diseases

Neoplasms
Malignant Neoplasms
Neoplasms, Germ Cell And Embryonal
Testicular Neoplasms
Germ Cell Tumor
Testicular Germ Cell Tumor
Malignant Neoplasm Of Testis
Carcinoma
Malignant Germ Cell Tumor
Neoplasm Metastasis
Teratoma
Intratubular Malignant Germ Cells
Neoplasm Invasiveness

Infertility
Carcinoma In Situ
Epithelial Ovarian Cancer
Ovarian Neoplasm
Hepatic Veno-occlusive Disease
Testicular Dysplasia
Precancerous Conditions

Pathways

Methylation
Chromatin Remodeling
Gene Silencing
Heterochromatin Assembly
Cell Development
Dna Methylation
Sex Determination
Localization
Embryo Development
Senescence

Germ Cell Development
Cell Cycle
Chromatin Modification
Histone Methylation

PTMs

Methylation

Sumoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Atf7ip

References

PMID: 10777215 by De Graeve F., et al. A murine ATFa-associated factor with transcriptional repressing activity.

PMID: 14536086 by Wang H., et al. mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression.