ASH1L Antibodies

AND ASH1L ELISA kits, ASH1L Proteins

Many biological assays use antibodies to detect ASH1L, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ASH1L in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ASH1L antibodies...

We validate the specificity of these antibodies to ASH1L by testing them on tissues known to express ASH1L positively and negatively. Browse below to find the ASH1L antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ASH1L Infographic by Boster Bio

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ASH1L Overview

Facts about Histone-lysine N-methyltransferase ASH1L.

Histone-lysine N-methyltransferase ASH1L (ASH1L)

Histone methyltransferase specifically methylating 'Lys- 36' of histone H3 (H3K36me). .

Gene Information

Human
Gene Name:	ASH1L
Uniprot:	Q9NR48
Entrez:	55870

Family

Belongs to:

class V-like SAM-binding methyltransferase superfamily

Alternative Names

Absent small and homeotic disks protein 1 homolog; ash1 (absent, small, or homeotic)-like (Drosophila); ASH1; ASH1L1; ASH1-like protein; EC 2.1.1.43; FLJ10504; huASH1; KMT2HKIAA1420; Lysine N-methyltransferase 2H; probable histone-lysine N-methyltransferase ASH1L

Molecular Weight

Mass (kDA):
332.79 kDA

Genomic Context


Human

Location:	1q22
Sequence:	1; NC_000001.11 (155335263..155563160, complement)

Tissue Specificity

Widely expressed, with highest level in brain, heart and kidney.

Subcellular Localizations

Nucleus. Cell junction, tight junction. Chromosome. The relevance of tight junction localization is however unclear.

Diseases

Neoplasms
Malignant Neoplasms
Malignant Neoplasm Of Lung
Carcinoma
Lung Neoplasms
Small Cell Carcinoma Of Lung
Adenoma
Muscular Dystrophy, Facioscapulohumeral
Carcinogenesis
Pituitary Diseases
Pituitary Neoplasms
Prolactinoma

Adenocarcinoma
Dystrophy
Hyperplasia
Muscular Dystrophy
Keratosis Follicularis
Malignant Carcinoid Syndrome
Trinucleotide Repeat Expansion

Pathways

Methylation
Chromatin Remodeling
Localization
Transport
Cell Adhesion
Cell Proliferation
Neurogenesis
Regulation Of Gene Expression
Cell Division
Translation
Cell Cycle

Cell Differentiation
Cell Growth
Histone Lysine Methylation
Segmentation
Pathogenesis

PTMs

Methylation

Phosphorylation

Deacetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ASH1L

References

PMID: 10860993 by Nakamura T., et al. huASH1 protein, a putative transcription factor encoded by a human homologue of the Drosophila ash1 gene, localizes to both nuclei and cell-cell tight junctions.

PMID: 22939622 by Pinheiro I., et al. Prdm3 and Prdm16 are H3K9me1 methyltransferases required for mammalian heterochromatin integrity.