ECE2 Antibodies

AND ECE2 ELISA kits, ECE2 Proteins

Many biological assays use antibodies to detect ECE2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ECE2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ECE2 antibodies...

We validate the specificity of these antibodies to ECE2 by testing them on tissues known to express ECE2 positively and negatively. Browse below to find the ECE2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ECE2 Infographic by Boster Bio

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Anti-ECE2 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A07406
100ul

ECE2 Overview

Facts about Endothelin-converting enzyme 2.

ECE2 3D structure. Source: alphafold

Endothelin-converting enzyme 2 (ECE2)

Converts big endothelin-1 into endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides.

May play a role in amyloid-beta processing (By similarity). .

Gene Information

Human
Gene Name:	ECE2
Uniprot:	P0DPD6
Entrez:	9718

Family

Belongs to:

peptidase M13 family

Alternative Names

EC 3.4.24; EC 3.4.24.71; ECE2; ECE-2; endothelin converting enzyme 2; endothelin-converting enzyme 2; KIAA0604MGC2408; MGC17664; MGC78487

Molecular Weight

Mass (kDA):
91.211 kDA

Genomic Context


Human

Location:	3q27.1
Sequence:	3; NC_000003.12 (184276022..184293031)

Subcellular Localizations

Golgi apparatus membrane; Single-pass type II membrane protein. Cytoplasmic vesicle, secretory vesicle membrane.

Diseases

Alzheimer's Disease
Neuroblastoma
Hypertensive Disease
Essential Hypertension
Stenosis
Nervousness
Dental Plaque
Dementia
Nervous System Disorder

Inflammation
Atherosclerosis
Persistant Generalized Lymphadenopathy

Pathways

System Development
Ovulation
Pathogenesis
Localization
Transdifferentiation
Anatomical Structure Development
Nervous System Development

Insemination
Embryo Development

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ECE2

References

PMID: 11718899 by Lorenzo M.-N., et al. Human endothelin converting enzyme-2 (ECE2): characterization of mRNA species and chromosomal localization.

PMID: 12560336 by Mzhavia N., et al. Characterization of endothelin-converting enzyme-2. Implication for a role in the nonclassical processing of regulatory peptides.