AP-3 complex subunit mu-2 Antibodies

AND AP3M2 ELISA kits, AP-3 complex subunit mu-2 Proteins

Many biological assays use antibodies to detect AP-3 complex subunit mu-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AP-3 complex subunit mu-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AP-3 complex subunit mu-2 antibodies...

We validate the specificity of these antibodies to AP-3 complex subunit mu-2 by testing them on tissues known to express AP3M2 positively and negatively. Browse below to find the AP3M2 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AP3M2 Infographic by Boster Bio

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AP3M2 Overview

Facts about AP-3 complex subunit mu-2.

AP3M2 3D structure. Source: alphafold

AP-3 complex subunit mu-2 (AP3M2)

Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures.

It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

Gene Information

Human
Gene Name:	AP3M2
Uniprot:	P53677
Entrez:	10947

Family

Belongs to:

adaptor complexes medium subunit family

Alternative Names

Adapter-related protein complex 3 mu-2 subunit; adaptor-related protein complex 3, mu 2 subunit; AP-3 complex subunit mu-2; AP47B; CLA20; Clathrin assembly protein assembly protein complex 1 medium chain homolog 2; Clathrin coat assembly protein AP47 homolog 2; Clathrin coat-associated protein AP47 homolog 2; clathrin-associated protein AP47 homolog 2; Golgi adaptor AP-1 47 kDa protein homolog 2; HA1 47 kDa subunit homolog 2; HA1 47kDA subunit homolog 2; mu3B-adaptin; P47B

Molecular Weight

Mass (kDA):
46.977 kDA

Genomic Context


Human

Location:	8p11.21
Sequence:	8; NC_000008.11 (42152946..42171183)

Subcellular Localizations

Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.

Diseases

Epilepsy
Immunologic Deficiency Syndromes
Albinism, Oculocutaneous
Nervousness
Hiv Infections
Chimera Disorder

Febrile Convulsions

Pathways

Endocytosis
Clathrin-mediated Endocytosis
Clathrin Coat Assembly
Receptor-mediated Endocytosis
Cell Activation
T Cell Activation
Pigmentation

Localization

PTMs

Phosphorylation

Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AP3M2

References

PMID: 7601449 by Koyama K., et al. Isolation of 115 human chromosome 8-specific expressed-sequence tags by exon amplification.