DENND4A Antibodies

AND DENND4A ELISA kits, DENND4A Proteins

Many biological assays use antibodies to detect DENND4A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DENND4A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DENND4A antibodies...

We validate the specificity of these antibodies to DENND4A by testing them on tissues known to express DENND4A positively and negatively. Browse below to find the DENND4A antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DENND4A Infographic by Boster Bio

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Anti-C-myc promoter-binding protein DENND4A Antibody

Human, Mouse

$405
Cat # A11173
100ul

DENND4A Overview

Facts about C-myc promoter-binding protein.

DENND4A 3D structure. Source: alphafold

C-myc promoter-binding protein (DENND4A)

Probable guanine nucleotide exchange factor (GEF) which may activate RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins in their active GTP- bound form.

According to PubMed:8056341, it may bind to ISRE-like component (interferon-stimulated response component ) of MYC P2 promoter. .

Gene Information

Human
Gene Name:	DENND4A
Uniprot:	Q7Z401
Entrez:	10260

Family

Belongs to:

No superfamily

Alternative Names

C-myc promoter-binding protein

Molecular Weight

Mass (kDA):
209.244 kDA

Genomic Context


Human

Location:	15q22.31
Sequence:	15; NC_000015.10 (65655234..65792293, complement)

Tissue Specificity

Expressed ubiquitously. Highest expression in bone marrow, medium in peripheral blood lymphocytes and lowest in spleen. In brain, breast, and prostate, higher expression was seen in normal cells than in tumor cells. Expression is regulated in a growth- and cell cycle-dependent manner.

Subcellular Localizations

Nucleus.

Interacting Proteins

YWHAZ

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DENND4A

References

PMID: 12906859 by Semova N., et al. Molecular cloning, structural analysis, and expression of a human IRLB, MYC promoter-binding protein: new DENN domain-containing protein family emerges.

PMID: 8056341 by Stasiv Y.Z., et al. Cloning of a cDNA encoding a human protein which binds a sequence in the c-myc gene similar to the interferon-stimulated response element.