Anti-ZGPAT Antibody

Product Name

Anti-ZGPAT Antibody

View all ZGPAT Antibodies

SKU/Catalog Number

A11540

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-ZGPAT Antibody (Catalog # A11540). Tested in ELISA, WB, IF applications. This antibody reacts with Human.

Storage & Handling

ZGPAT antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-ZGPAT Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A11540)

Host

Chicken

Contents

ZGPAT Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgY

Immunogen

ZGPAT antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human ZGPAT. The immunogen is located within the last 50 amino acids of ZGPAT.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

Multiple isoforms of ZGPAT are known to exist.

Reactive Species

A11540 is reactive to ZGPAT in Human

Reconstitution

Calculated molecular weight

57359 MW

Background of ZGPAT

The Zinc finger CCCH-type with G patch domain-containing protein (ZGPAT), is a transcriptional repressor that regulates several cellular pathways including EGFR pathways that are involved in cell proliferation, migration and survival. ZGPAT recruits the Mi-2/NuRD complex and represses the expression of EGFR. ZGPAT is down-regulated in breast carcinomas and its expression is negatively correlated with that of EGFR, suggesting that it may be a potential target for breast cancer therapy. Multiple isoforms of ZGPAT are known to exist, including sZIP, which binds to the Mi-2/NuRD complex but lacks the DNA binding component of full-length ZGPAT, thereby antagonizing transcription repression and growth inhibition by ZGPAT.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A11540 is guaranteed for ELISA, IF, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

ZGPAT antibody can be used for detection of ZGPAT by Western blot at 1 μg/mL. Antibody can also be used for immunofluorescence starting at 20 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For ZGPAT (Source: Uniprot.org, NCBI)

Alternative Names

ZIP, ZC3H9, GPATC6, GPATCH6, ZC3HDC9, KIAA1847, ZIP, Zinc finger CCCH-type with G patch domain-containing protein, G patch domain-containing protein 6 ZGPAT GPATC6, GPATCH6, KIAA1847, ZC3H9, ZC3HDC9, ZIP zinc finger CCCH-type and G-patch domain containing zinc finger CCCH-type with G patch domain-containing protein|g patch domain-containing protein 6|zinc finger CCCH domain-containing protein 9|zinc finger and G patch domain-containing protein|zinc finger, CCCH-type with G patch domain

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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