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Product Info Summary
| SKU: | A04199 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, ICC, WB |
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Product info
Product Name
Anti-ZC3HAV1 Antibody
SKU/Catalog Number
A04199
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-ZC3HAV1 Antibody (Catalog # A04199). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human.
Storage & Handling
ZC3HAV1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-ZC3HAV1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04199)
Host
Rabbit
Contents
ZC3HAV1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
ZC3HAV1 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human ZC3HAV1. The immunogen is located within amino acids 680 - 730 of ZC3HAV1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least two isoforms of TSLP-R are known to exist; this antibody will recognize both isoforms.
Reactive Species
A04199 is reactive to ZC3HAV1 in Human
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
101431 MW
Background of ZCCHV
The zinc finger antiviral protein (ZC3HAV1) is a CCCH type zinc finger protein that induces an innate immunity to infections by retrovirus by preventing the accumulation of viral RNAs in the cytoplasm and recruits the RNA processing exosome to degrade target RNAs, thereby inhibiting virus replication. ZC3HAV1 is localized in the cytoplasm at steady state, but shuttles between nucleus and cytoplasm in a XPO1-dependent manner. ZAP is a direct target gene of IRF3 action in cellular antiviral responses.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A04199 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ZC3HAV1 antibody can be used for detection of ZC3HAV1 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 20 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of ZC3HAV1 in HeLa cell lysate with ZC3HAV1 antibody at 1μg/mL in (A) the absence and (B) the presence of blocking peptide.
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Immunocytochemistry of ZC3HAV1 in HeLa cells with ZC3HAV1 antibody at 20 μg/mL.
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Immunofluorescence of ZC3HAV1 in Hela cells with ZC3HAV1 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For ZC3HAV1 (Source: Uniprot.org, NCBI)
Gene Name
ZC3HAV1
Full Name
Zinc finger CCCH-type antiviral protein 1
Weight
101431 MW
Alternative Names
ZAP, ZC3H2, ARTD13, PARP13, FLB6421, ZC3HDC2, PRO1677, Zinc finger CCCH-type antiviral protein 1, ADP-ribosyltransferase diphtheria toxin-like 13 ZC3HAV1 ARTD13, FLB6421, PARP13, ZAP, ZC3H2, ZC3HDC2 zinc finger CCCH-type containing, antiviral 1 zinc finger CCCH-type antiviral protein 1|ADP-ribosyltransferase diphtheria toxin-like 13|inactive Poly [ADP-ribose] polymerase 13|zinc finger CCCH domain-containing protein 2|zinc finger CCCH-type, antiviral 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ZC3HAV1, check out the ZC3HAV1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ZC3HAV1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ZC3HAV1 Antibody (A04199)
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