Anti-WDR35 Antibody

Product Name

Anti-WDR35 Antibody

View all WDR35 Antibodies

SKU/Catalog Number

A07256

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-WDR35 Antibody (Catalog # A07256). Tested in ELISA, IHC-P applications. This antibody reacts with Human.

Storage & Handling

WDR35 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-WDR35 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07256)

Host

Rabbit

Contents

WDR35 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

WDR35 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human WDR35. The immunogen is located within amino acids 60 - 110 of WDR35.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

WDR35 antibody is human specific.

Reactive Species

A07256 is reactive to WDR35 in Human

Reconstitution

Observed Molecular Weight

68 kDa

Calculated molecular weight

133547 MW

Background of WDR35

WD40 repeats are a common structural module in eukaryotic proteins, and proteins containing WD40 domains have a wide range of functions, including signal transduction, cell cycle regulation, RNA splicing, and transcription. One such protein, WDR35, also known as CED2, has been shown to be mutated in patients with Sensenbrenner syndrome/cranioectodermal dysplasia (CED), an autosomal-recessive disease that is characterized by craniosynstosis and ectodermal and skeletal abnormalities. WDR35 localizes to cilia and dentrosomes during embryogenesis and human and mouse fibroblasts that lack this gene fail to produce cilia. Mutations in this gene can also cause short-rib polydactyly syndromes due to abnormal ciliogenesis.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Applications

A07256 is guaranteed for ELISA, IHC-P Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WDR35 antibody can be used for detection of WDR35 by immunohistochemistry at 5 μg/mL.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For WDR35 (Source: Uniprot.org, NCBI)

Alternative Names

CED2, IFTA1, SRTD7, IFT121, KIAA1336, WD repeat-containing protein 35, Intraflagellar transport protein 121 homolog WDR35 CED2, FAP118, IFT121, IFTA1, SRTD7 WD repeat domain 35 WD repeat-containing protein 35|intraflagellar transport protein 121 homolog|naofen

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

Here are featured tools and databases that you might find useful.

• Boster's Pathways Library
• Protein Databases
• Bioscience Research Protocol Resources
• Data Processing & Analysis Software
• Photo Editing Software
• Scientific Literature Resources
• Research Paper Management Tools
• Molecular Biology Software
• Primer Design Tools
• Bioinformatics Tools
• Phylogenetic Tree Analysis