Anti-TTC5 Antibody

Product Name

Anti-TTC5 Antibody

View all TTC5 Antibodies

SKU/Catalog Number

A13808

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-TTC5 Antibody (Catalog # A13808). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.

Storage & Handling

TTC5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-TTC5 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A13808)

Host

Rabbit

Contents

TTC5 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

TTC5 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human TTC5. The immunogen is located within the last 50 amino acids of TTC5.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

At least two isoforms of Paralemmin3 are known to exist; this antibody will only detect the longer isoform

Reactive Species

A13808 is reactive to TTC5 in Human, Mouse

Reconstitution

Observed Molecular Weight

68 kDa

Calculated molecular weight

48928 MW

Background of TTC5

Tetratricopeptide repeat protein 5 (TTC5) is a member of a diverse group of functionally distinct proteins that are characterized by containing one or more tetratricopeptide repeats. Each motif consists of two anti-parallel a-helices such that tandem arrays of TPR motifs generate a right-handed helical structure with an amphipathic channel that may serve to accommodate the complementary region of a target protein. While the exact function of TTC5 remains unclear, it is thought that the TPR motifs serve to mediate protein-protein interactions such as those seen with protein chaperones HSP70 and HSP90 and some proteins involved in cell stress response signaling pathways such as protein phosphatase 5, suggesting that TTC5 may also function via protein-protein interactions mediated by its TPR motifs.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Applications

A13808 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

TTC5 antibody can be used for the detection of TTC5 by Western blot at 0.5 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For TTC5 (Source: Uniprot.org, NCBI)

Alternative Names

Strap, Tetratricopeptide repeat protein 5, Stress-responsive activator of p300, TPR repeat protein 5 TTC5 Strap tetratricopeptide repeat domain 5 tetratricopeptide repeat protein 5|TPR repeat protein 5|stress-responsive activator of p300

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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