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Product Info Summary
| SKU: | A15776 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-Transmembrane protein 184C TMEM184C Antibody
SKU/Catalog Number
A15776
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Transmembrane protein 184C TMEM184C Antibody (Catalog # A15776). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
TMEM184C antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Transmembrane protein 184C TMEM184C Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A15776)
Host
Rabbit
Contents
TMEM184C Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
TMEM184C antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human TMEM184C. The immunogen is located within amino acids 340 - 390 of TMEM184C.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least two alternatively spliced transcript variants have been observed.
Reactive Species
A15776 is reactive to TMEM184C in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
50142 MW
Background of TMEM184C
Anaplastic thyroid cancer is one of the most lethal forms of cancer, but the precise carcinogenic mechanism has not been identified. TMEM184C, also known as TMEM34, was identified in a cDNA microarray analysis as being down-regulated in anaplastic thyroid cancers compared to normal thyroid tissues. TMEM184C protein expression was also lower in cell lines derived from these types of cancers compared to that of normal thyroid tissues or cell lines based on other types of thyroid cancers. Furthermore, transfection of TMEM34 into KTA2 cells led to the inhibition of cell growth, suggesting that TMEM184C might act as a tumor suppressor in anaplastic thyroid cancers.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A15776 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
TMEM184C antibody can be used for detection of TMEM184C by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of TMEM184C in mouse heart tissue lysate with TMEM184C antibody at 1 μg/mL.
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Immunohistochemistry of TMEM184C in mouse heart tissue with TMEM184C antibody at 5 μg/mL.
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Immunofluorescence of TMEM184C in mouse heart tissue with TMEM184B antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For TMEM184C (Source: Uniprot.org, NCBI)
Gene Name
TMEM184C
Full Name
Transmembrane protein 184C
Weight
50142 MW
Superfamily
TMEM184 family
Alternative Names
TMEM34, TMEM34, PRO1355, Transmembrane protein 184C, Transmembrane protein 34 TMEM184C TMEM34 transmembrane protein 184C transmembrane protein 184C|transmembrane protein 34
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TMEM184C, check out the TMEM184C Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TMEM184C: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Transmembrane protein 184C TMEM184C Antibody (A15776)
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