Anti-Transmembrane protein 184C TMEM184C Antibody

Product Name

Anti-Transmembrane protein 184C TMEM184C Antibody

View all TMEM184C Antibodies

SKU/Catalog Number

A15776

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Transmembrane protein 184C TMEM184C Antibody (Catalog # A15776). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

TMEM184C antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-Transmembrane protein 184C TMEM184C Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A15776)

Host

Rabbit

Contents

TMEM184C Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

TMEM184C antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human TMEM184C. The immunogen is located within amino acids 340 - 390 of TMEM184C.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

At least two alternatively spliced transcript variants have been observed.

Reactive Species

A15776 is reactive to TMEM184C in Human, Mouse, Rat

Reconstitution

Observed Molecular Weight

68 kDa

Calculated molecular weight

50142 MW

Background of TMEM184C

Anaplastic thyroid cancer is one of the most lethal forms of cancer, but the precise carcinogenic mechanism has not been identified. TMEM184C, also known as TMEM34, was identified in a cDNA microarray analysis as being down-regulated in anaplastic thyroid cancers compared to normal thyroid tissues. TMEM184C protein expression was also lower in cell lines derived from these types of cancers compared to that of normal thyroid tissues or cell lines based on other types of thyroid cancers. Furthermore, transfection of TMEM34 into KTA2 cells led to the inhibition of cell growth, suggesting that TMEM184C might act as a tumor suppressor in anaplastic thyroid cancers.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A15776 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

TMEM184C antibody can be used for detection of TMEM184C by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For TMEM184C (Source: Uniprot.org, NCBI)

Alternative Names

TMEM34, TMEM34, PRO1355, Transmembrane protein 184C, Transmembrane protein 34 TMEM184C TMEM34 transmembrane protein 184C transmembrane protein 184C|transmembrane protein 34

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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