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Product Info Summary
| SKU: | A12774 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-Transmembrane protein 184B TMEM184B Antibody
SKU/Catalog Number
A12774
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Transmembrane protein 184B TMEM184B Antibody (Catalog # A12774). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
TMEM184B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Transmembrane protein 184B TMEM184B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12774)
Host
Rabbit
Contents
TMEM184B Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
TMEM184B antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human TMEM184B. The immunogen is located within the last 50 amino acids of TMEM184B.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least two isoforms of LRFN5 are known to exist. This antibody is predicted to not cross-react with other members of the LRFN family.
Reactive Species
A12774 is reactive to TMEM184B in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
45562 MW
Background of TMEM184B
TMEM184B, also known as C22orf5, is a 407 amino acid multi-pass membrane protein and represents a novel gene in the activation of the MAPK signaling pathway. The gene encoding TMEM184B maps to human chromosome 22; mutations in several of the genes in chromosome 22 are involved in the development of autism, schizophrenia, Phelan-McDermid syndrome and Neurofibromatosis type 2, suggesting that TMEM184B may play a role in these syndromes.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A12774 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
TMEM184B antibody can be used for detection of TMEM184B by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of TMEM184B in rat lung tissue lysate with TMEM184B antibody at (A) 1 and (B) 2 μg/mL.
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Immunohistochemistry of TMEM184B in human lung tissue with TMEM184B antibody at 5 μg/mL.
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Immunofluorescence of TMEM184B in human lung tissue with TMEM184B antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For TMEM184B (Source: Uniprot.org, NCBI)
Gene Name
TMEM184B
Full Name
Transmembrane protein 184B
Weight
45562 MW
Superfamily
TMEM184 family
Alternative Names
FM08, HS5O6A, C22orf5, PSEC0108, Transmembrane protein 184B, Putative MAPK-activating protein FM08 TMEM184B C22orf5, FM08, HS5O6A, HSPC256 transmembrane protein 184B transmembrane protein 184B|putative MAPK-activating protein FM08
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TMEM184B, check out the TMEM184B Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TMEM184B: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Transmembrane protein 184B TMEM184B Antibody (A12774)
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