Product Info Summary
SKU: | A08441 |
---|---|
Size: | 100 µg |
Reactive Species: | Human |
Host: | Rabbit |
Application: | IHC, WB |
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Product info
Product Name
Anti-TOX Antibody
SKU/Catalog Number
A08441
Size
100 µg
Form
Liquid
Description
Boster Bio Anti-TOX Antibody (Catalog# A08441). Tested in IHC, WB application(s). This antibody reacts with Human.
Storage & Handling
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Cite This Product
Anti-TOX Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08441)
Host
Rabbit
Contents
100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A partial length recombinant TOX protein (amino acids 450-525)
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A08441 is reactive to TOX in Human
Reconstitution
Calculated molecular weight
57513 MW
Background of TOX
SmarcAL1 (SWI/SNF-related µatrix-associated actin-dependent regulator of chromatin a-like 1) is also known as HARP, HepA Related Protein, HHARP, SMARCA like Protein 1 and SWI/SNF Related. SmarcAL1 is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein shows sequence similarity to the E. coli RNA polymerase-binding protein HepA. Mutations in this gene are a cause of Schimke immunoosseous dysplasia (SIOD), an autosomal recessive disorder with the diagnostic features of spondyloepiphyseal dysplasia, renal dysfunction, and T-cell immunodeficiency.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A08441 is guaranteed for IHC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blot: 2-4 µg/ml
IHC: 5 µg/ml
Validation Images & Assay Conditions
Click image to see more details
Immunohistochemical analysis of TOX. Anti-TOX antibody in human Testis tissue at 5 &mu
Click image to see more details
Western blot analysis of TOX. Anti-TOX antibody was used at 2 &mu
Protein Target Info & Infographic
Gene/Protein Information For TOX (Source: Uniprot.org, NCBI)
Gene Name
TOX
Full Name
Thymocyte selection-associated high mobility group box protein TOX
Weight
57513 MW
Alternative Names
Thymocyte selection-associated high mobility group box protein TOX;Thymus high mobility group box protein TOX;TOX;KIAA0808; TOX TOX1 thymocyte selection associated high mobility group box thymocyte selection-associated high mobility group box protein TOX|thymus high mobility group box protein TOX
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TOX, check out the TOX Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TOX: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-TOX Antibody (A08441)
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No publications found for A08441
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Customer Reviews
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Customer Q&As
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5 Customer Q&As for Anti-TOX Antibody
Question
Would anti-TOX antibody A08441 work on feline IHC with brain?
Verified Customer
Verified customer
Asked: 2020-04-30
Answer
Our lab technicians have not tested anti-TOX antibody A08441 on feline. You can run a BLAST between feline and the immunogen sequence of anti-TOX antibody A08441 to see if they may cross-react. If the sequence homology is close, then you can perform a pilot test. Keep in mind that since we have not validated feline samples, this use of the antibody is not covered by our guarantee. However we have an innovator award program that if you test this antibody and show it works in feline brain in IHC, you can get your next antibody for free.
Boster Scientific Support
Answered: 2020-04-30
Question
Thank you for helping with my inquiry over the phone. Here are the WB image, lot number and protocol we used for brain using anti-TOX antibody A08441. Let me know if you need anything else.
Verified Customer
Verified customer
Asked: 2020-03-16
Answer
We appreciate the data. You have provided everything we needed. Our lab team are working to resolve your inquiry as quickly as possible, and we appreciate your patience and understanding! Please let me know if there is anything you need in the meantime.
Boster Scientific Support
Answered: 2020-03-16
Question
We are currently using anti-TOX antibody A08441 for human tissue, and we are content with the IHC results. The species of reactivity given in the datasheet says human. Is it true that the antibody can work on primate tissues as well?
A. Taylor
Verified customer
Asked: 2020-03-11
Answer
The anti-TOX antibody (A08441) has not been tested for cross reactivity specifically with primate tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in primate you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2020-03-11
Question
I see that the anti-TOX antibody A08441 works with IHC, what is the protocol used to produce the result images on the product page?
Verified Customer
Verified customer
Asked: 2019-10-11
Answer
You can find protocols for IHC on the "support/technical resources" section of our navigation menu. If you have any further questions, please send an email to [email protected]
Boster Scientific Support
Answered: 2019-10-11
Question
Is a blocking peptide available for product anti-TOX antibody (A08441)?
Verified Customer
Verified customer
Asked: 2019-08-29
Answer
We do provide the blocking peptide for product anti-TOX antibody (A08441). If you would like to place an order for it please contact [email protected] and make a special request.
Boster Scientific Support
Answered: 2019-08-29