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Product Info Summary
| SKU: | A01541-1 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, IF, ICC, WB |
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Product info
Product Name
Anti-Toll-like receptor 8 TLR8 Antibody
SKU/Catalog Number
A01541-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Toll-like receptor 8 TLR8 Antibody (Catalog # A01541-1). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human, Mouse.
Storage & Handling
TLR8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Toll-like receptor 8 TLR8 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01541-1)
Host
Rabbit
Contents
TLR8 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
TLR8 antibody was raised against a peptide corresponding to 16 amino acids near the middle of human TLR8. The immunogen is located within amino acids 790 - 840 of TLR8.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least three isoforms of TLR8 are known to exist. TLR8 antibody is predicted to not cross-react with other TLR protein family members
Reactive Species
A01541-1 is reactive to TLR8 in Human, Mouse
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
119828 MW
Background of TLR8
Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. Like TLR7, TLR8 is localized to endosomal or lysosomal compartments and stimulates the innate immune response after activation by guanosine- and uridine-rich single-stranded RNA. Human but not murine TLR8 confers responsiveness to the antiviral compound R-848.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A01541-1 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
TLR8 antibody can be used for detection of TLR8 by Western blot at 0.5 to 2 μg/mL. Antibody can also be used for immunocytochemistry starting at 2 μg/mL. For immunofluorescence start at 10 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of TLR8 in Daudi cell lysates with TLR8 antibody at (A) 0.5
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Immunocytochemistry of TLR8 in Daudi cells with TLR8 antibody at 2 μg/mL.
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Immunofluorescence of TLR8 in Daudi cells with TLR8 antibody at 10 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For TLR8 (Source: Uniprot.org, NCBI)
Gene Name
TLR8
Full Name
Toll-like receptor 8
Weight
119828 MW
Superfamily
Toll-like receptor family
Alternative Names
CD288, Toll-like receptor 8 TLR8 CD288 toll like receptor 8 toll-like receptor 8
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TLR8, check out the TLR8 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TLR8: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Toll-like receptor 8 TLR8 Antibody (A01541-1)
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