Anti-Toll-like receptor 1 TLR1 Antibody Picoband®

Product Name

Anti-Toll-like receptor 1 TLR1 Antibody Picoband®

View all TLR1 Antibodies

SKU/Catalog Number

PA2246

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Toll-like receptor 1 TLR1 Antibody catalog # PA2246. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Toll-like receptor 1 TLR1 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2246)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human TLR1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA2246 is reactive to TLR1 in Human

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

90 kDa

Calculated molecular weight

90291 MW

Background of TLR1

Toll-like receptor 1 (TLR1), also called TIL or CD281 is a member of the Toll-like receptor family (TLR) of pattern recognition receptors of the innate immune system. This gene is mapped to 4p14 by fluorescence in situ hybridization. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PA2246 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human

Positive Control

WB: COLO320 Whole Cell, SW620 Whole Cell, SKOV Whole Cell, JURKAT Whole Cell, CEM Whole Cell, PANC Whole Cell

Validation Images & Assay Conditions

Gene/Protein Information For TLR1 (Source: Uniprot.org, NCBI)

Alternative Names

Toll-like receptor 1;Toll/interleukin-1 receptor-like protein;TIL;CD281;TLR1;KIAA0012; TLR1 CD281, TIL, TIL. LPRS5, rsc786 toll like receptor 1 toll-like receptor 1|toll/interleukin-1 receptor-like protein

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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