Anti-TIRP TICAM2 Antibody

Product Name

Anti-TIRP TICAM2 Antibody

View all TRAM/TICAM2 Antibodies

SKU/Catalog Number

A03965-2

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-TIRP TICAM2 Antibody (Catalog # A03965-2). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human.

Storage & Handling

TIRP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-TIRP TICAM2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03965-2)

Host

Rabbit

Contents

TIRP Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

TIRP antibody was raised against a peptide corresponding to 16 amino acids at the C-terminus of human TIRP. The immunogen is located within the last 50 amino acids of TIRP.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

At least four isoforms of RABEX5 are known to exist; this antibody will recognize all four. RABEX5 antibody is predicted to not cross-react with other LRRFIP family members.

Reactive Species

A03965-2 is reactive to TICAM2 in Human

Reconstitution

Observed Molecular Weight

68 kDa

Calculated molecular weight

26916 MW

Background of TRAM/TICAM2

TIRP is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TIRP, along with other molecules such as TRIF, MAL, and MyD88, serves as an adaptor protein that allows for the interaction and activation of the IL-1R-associated kinase (IRAK) family, the subsequent activation of TNF receptor associated factor (TRAF)-6, and ultimately the activation of NF-κB. Expression of TIRP appears to be essential for TLR4 signalling.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Applications

A03965-2 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

TIRP antibody can be used for detection of TIRP by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 10 μg/mL. For immunofluorescence start at 10 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For TICAM2 (Source: Uniprot.org, NCBI)

Alternative Names

TIRP, TRAM, TIRAP3, MyD88-4, TICAM-2, TIRP, TIR domain-containing adapter molecule 2, Putative NF-kappa-B-activating protein 502 Ticam2|B430113A10, T, TICAM-2, TR, TRAM, Tirp, Trif|toll-like receptor adaptor molecule 2|TIR domain-containing adapter molecule 2|TIR domain-containing adapter protein|TRIF-related adapter molecule TRAM|TRIF-related adaptor molecule|Toll-interleukin I receptor domain (TIR)-containing adaptor molecule (TICAM) 2|toll/interleukin-1 receptor domain-containing protein

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

Here are featured tools and databases that you might find useful.

• Boster's Pathways Library
• Protein Databases
• Bioscience Research Protocol Resources
• Data Processing & Analysis Software
• Photo Editing Software
• Scientific Literature Resources
• Research Paper Management Tools
• Molecular Biology Software
• Primer Design Tools
• Bioinformatics Tools
• Phylogenetic Tree Analysis